by Roche.History[edit]The racemic parent compound racemorphan was first described in a Swiss and US patent application from Hoffmann-La Roche in 1946 and 1947, respectively; a patent was granted in 1950. A resolution of the two isomers of racemorphan with tartaric acid was published in 1952,[41] and dextromethorphan was successfully tested in 1954 as part of US Navy and CIA-funded research on nonaddictive