Effects of sufentanil on immune response, pain mediators and brain-sparing effect in patients with breast cancer undergoing radicalmastectomy. To investigate the effects of sufentanil on immune response, pain mediators and brain-sparing effect in patients with breast cancer undergoing radicalmastectomy. This study was a single center retrospective cohort study. The 118 study subjects were
Hydromorphone combined with ropivacaine for erector spinae plane block in patients undergoing modified radicalmastectomy: A prospective randomized controlled trial. Combining hydromorphone with ropivacaine in ultrasound-guided erector spinae plane blocks enhances postoperative analgesia and reduces interleukin-6 expression in breast surgery patients. In this study, breast cancer patients undergoing modified radicalmastectomy were randomized into 3 groups for anesthesia (30 patients in each group): standard general (group C), Erector Spinae Plane Block (ESPB) with ropivacaine (group R), and ESPB with ropivacaine plus hydromorphone (group HR). Diagnosis: Breast cancer patients. Postsurgery, pain levels, IL-6, anesthetic doses, additional analgesia needs, and recovery milestones were
Comparison of midpoint transverse process to pleura (MTP) block and erector spinae plane block (ESP) for postoperative analgesia in modified radicalmastectomy patients: A double-blinded, randomized control trial. Modified radicalmastectomy (MRM) is associated with moderate severity of postoperative pain. Besides intravenous (IV) analgesics, various nerve blocks are being described for pain
Role of tramadol as an adjuvant in ultrasound-guided serratus anterior muscle block for modified radicalmastectomy - A randomized control trial. Modified radicalmastectomy (MRM) is associated with significant acute post-operative pain that may progress to chronic pain syndromes in 25-60% of patients. Serratus anterior muscle (SAM) block has proved to be an excellent analgesic option
The Prevention of Seroma Formation Following Modified RadicalMastectomy by Intravenous Hydrocortisone Injection. Introduction Seroma formation is the most common complication after modified radicalmastectomy (MRM). It leads to increased pain and discomfort, potentially prolonging morbidity and treatment. Various treatment modalities are being used to decrease the incidence of seroma formation
Comparison Between Erector Spinae Plane Block versus Serratus Anterior Plane Block Regarding Analgesia and Stress Response After Modified RadicalMastectomy: Randomized Controlled Trial. Modified radicalmastectomy (MRM) is the primary surgical treatment for breast cancer, yet it leads to significant postoperative pain. This randomized controlled trial evaluates the effects of an erector spinae
The Implementation and Effectiveness of Progressive Rehabilitation Nursing on Quality of Life, Self-Care Ability, and Psychological Status in Patients with Breast Cancer after Modified RadicalMastectomy. To evaluate the implementation and effectiveness of progressive rehabilitation nursing in patients undergoing modified radicalmastectomy for breast cancer. A total of 70 patients undergoing modified radicalmastectomy for breast cancer in our hospital were selected as the research subjects, and they were randomly divided into a control group and an observation group, with 35 patients in each group. The control group received routine rehabilitation nursing intervention after surgery, while the observation group received progressive rehabilitation nursing intervention based on the control
Effects of a single subanesthetic dose of esketamine on postoperative subthreshold depressive symptoms in patients undergoing unilateral modified radicalmastectomy: a randomised, controlled, double-blind trial. Breast cancer is the most common malignant tumor in females worldwide. During disease development, breast cancer patients suffer anxious and depressed, which may lead to worse quality of life or even higher mortality. Esketamine has been regarded as an antidepressant in breast cancer patients with mild or moderate depression. Here, we wonder whether the administration of esketamine could reduce the postoperative depressive symptom score of breast cancer patients who have no preoperative depression. A total of 64 patients treated with unilateral modified radicalmastectomy were
Comparison of Analgesic Efficacy of Ultrasound Guided PEC II Block Using Dexamethasone as an Adjuvant to Ropivacaine Versus Plain Ropivacaine in Patients Undergoing Modified RadicalMastectomy: A Double-Blind, Randomized Controlled Trial. Pain after breast cancer surgery is one of the main reasons for postoperative morbidity and pulmonary complications leading to increased hospital stay being used to address acute postoperative pain after breast cancer surgery. However, to date, not many studies have been done regarding prolonging the duration of analgesia of PEC II blocks for postoperative pain relief in patients undergoing modified radicalmastectomy (MRM). So, we undertook this study to compare the analgesic efficacy of PEC II block using dexamethasone as an adjuvant
Comparative evaluation of continuous infusion versus programmed intermittent bolus techniques in erector spinae plane block in modified radicalmastectomy - A preliminary randomised controlled trial. Single-shot erector spinae plane block (ESPB) provides excellent analgesia in mastectomy in the immediate post-operative period but is not sufficient to maintain for prolonged duration. This study
A comparative study of respiratory effects of erector spinae plane block versus paravertebral plane block for women undergoing modified radicalmastectomy. Inadequate acute postoperative pain control after modified radicalmastectomy (MRM) can compromise pulmonary function. This work aimed to assess the postoperative pulmonary effects of a single-shot thoracic paravertebral block (TPVB
Effect of music therapy combined with aerobic exercise on sleep quality among breast cancer patients undergoing chemotherapy after a radicalmastectomy: a randomized controlled trial. We aimed to study the effect of music therapy combined with aerobic exercise on the sleep quality of patients undergoing chemotherapy after a radicalmastectomy. A randomized controlled trial was conducted at the Breast Disease Diagnosis and Treatment Center, Shaanxi Province Tumor Hospital, from July 2017 to June 2019. 110 female breast cancer patients who underwent a radicalmastectomy were recruited and randomly allocated into an intervention group or a control group. The intervention group completed music therapy combined with aerobic exercise from the first to the sixth admission to the hospital
Comparison between ultrasound guided erector spinae plane block and paravertebral block on acute and chronic post mastectomy pain after modified radicalmastectomy: randomized controlled trial. Inadequate acute postoperative pain management is linked to the effect on the stress response and development of chronic pain. A unique regional anaesthetic method that is becoming more important for postoperative pain management is erector spinea plane block (ESP). Since its initial description, physicians have questioned weather this novel easy method can take the place of paravertebral block (PVB). Our goal was to evaluate, in contrast to control group, the effects of ESP & PVB on acute and chronic post-mastectomy pain. One hundred and five female patients undergoing modified radicalmastectomy
Assessment of ultrasound guided erector spinae plane block for early post-operative analgesia for modified radicalmastectomy: a prospective, randomized, controlled study. Erector spinae plane block is a recently introduced block with a wide range of indications. The aim of the present study was to assess the efficacy and safety of ultrasound-guided erector spinae plane block on early post -operative pain relief in patients undergoing modified radicalmastectomy. We conducted a prospective, randomized, controlled study in a tertiary care institute. Sixty-five patients were enrolled. Final analysis was performed on 58 patients randomized into two groups. Ultrasound-guided erector spinae plane block with 25 mL of 0.25% bupivacaine was given using a 18 gauge needle. No block was given
Ultrasound-guided Double-point Versus Single-point Serratus Anterior Plane Block for Modified RadicalMastectomy: A Randomized Controlled Trial. The double-point serratus anterior plane block(SAPB) covers more area, including the axilla, than the single-point approach, potentially offering better pain relief after Modified radicalmastectomy(MRM). Sixty women were randomly assigned to double
Postoperative Analgesic Efficacy of Intraoperative Pectoral Nerve Block for Modified RadicalMastectomy: a Double-Blind Prospective Randomised Interventional Study. Severe acute postoperative pain following breast surgery increases the risk of persistent pain and affects the recovery of patients. Recently, pectoral nerve (PECs) block has gained significance as a regional fascial block that can provide adequate postoperative analgesia. This study aimed to evaluate the safety and efficacy of PECs II block, which was given intraoperative under direct vision after performing modified radicalmastectomy for breast cancer patients. This prospective randomised study was comprised of a PECs II group ( = 30) and a control group ( = 30). Group A patients received 25 ml of 0.25% bupivacaine for PECs II
Effects of S-ketamine on Postoperative Recovery Quality and Inflammatory Response in Patients Undergoing Modified RadicalMastectomy. S-ketamine plays an important role in reducing postoperative pain, but its impact on the quality of recovery in breast cancer has not been clarified. We designed this trial to explore the effects of s-ketamine on the quality of postoperative recovery and inflammatory response in modified radicalmastectomy. A total of 138 patients were randomly assigned to group C (group control), group K1 (group of s-ketamine dose 1) and group K2 (group of s-ketamine dose 2). Groups K1 and K2 were given 0.1 mg/kg, 0.2 mg/kg s-ketamine intravenous (IV) after induction, followed by 0.1 mg/kg/h or 0.2 mg/kg/h continuous intravenous infusion, respectively. Group C received
S-Ketamine attenuates inflammatory effect and modulates the immune response in patients undergoing modified radicalmastectomy: A prospective randomized controlled trial. This study aimed to investigate the impact of varying dosages of S-ketamine on perioperative immune-inflammatory responses in patients undergoing modified radicalmastectomy (MRM). This is a prospective, randomized
Analgesic effect of ketorolac as an adjuvant to bupivacaine in ultrasound-guided pectoral nerve block (I + II) for patients undergoing modified radicalmastectomy: A randomized controlled clinical trial. Many drugs have been tried as adjuvant to local anesthetic in different nerve blocks. Ketorolac is one of them, but it has never been used in pectoral nerve block. In this study, we evaluated its adjuvant effect with local anesthetic on postoperative analgesia in ultrasound (US)-guided pectoral nerve (PECS) blocks. The aim was to assess the quality and the duration of analgesia by the addition of ketorolac in the PECS block. 46 patients who underwent modified radicalmastectomies under general anesthesia were randomized into two groups: control group, where pectoral nerve block was given