Assessment of recurrentmiscarriage Skip to main contentSkip to searchLog inEnglishWe're showing you BMJ Best Practice in English. Click here to change your language.Please note: changing your language may affect units of measurement for drug dosages, drug names, spelling and choice of guidelines#{autosuggest.search}#{autosuggest.search}Assessment of recurrentmiscarriage MENULog , as prevalence of causes is similar in those with 2, 3, or more miscarriages.[3] Despite a wide range of investigations, no apparent cause is found in >50% of cases of recurrentmiscarriage.[4] About 70% of patients with no cause found will achieve a live birth in the subsequent pregnancy depending on the age of the woman and the number of previous miscarriages.[3][4][Figure caption and citation
[Exploration of CCL11 and sTNFR2 as potential biomarkers for the efficacy of lymphocyte immunotherapy in women with unexplained recurrentspontaneousabortion]. To explore biomarkers for the efficacy of lymphocyte immunotherapy (LIT) treating women with unexplained recurrentspontaneousabortion (URSA). Serum samples from 24 URSA potients who received LIT were collected at Peking University
RecurrentMiscarriage 16 19 25 34 200 400 In this guideline, recurrentmiscarriage has been defined as three or more first trimester miscarriages. However, clinicians are encouraged to use their clinical discretion recommend extensive evaluation after two miscarriages, if there is a suspicion that the miscarriages of pathological and not sporadic nature. Women with should be offered testing
Untargeted metabolomics analysis reveals the metabolic disturbances and exacerbation of oxidative stress in recurrentspontaneousabortion. Recurrentspontaneousabortion (RSA) is characterized by the occurrence of two or more consecutive spontaneous abortions, with a rising prevalence among pregnant women and significant implications for their physical and mental well-being. The multifaceted
Common mental disorders and risk of spontaneous abortion or recurrentspontaneousabortion: A two-sample Mendelian randomization study. The direct causal relationships between common mental disorders (anxiety disorders, broad depression, major depressive disorder (MDD), bipolar disorder, and insomnia) and miscarriage or recurrentspontaneousabortion (RSA) are unclear. Therefore, this study
[Study of plasma metabolic markers in unexplained recurrentspontaneousabortion based on non-target metabolomics approach]. To screen plasma metabolic markers in patients with unexplained recurrentspontaneousabortion (URSA) by non-target metabolomics approach. From September 2022 to May 2023, the plasma of 23 URSA pregnant women with threatened abortion who visited the outpatient clinic
Decidual stromal cell-derived exosomes deliver miR-22-5p_R-1 to suppress trophoblast metabolic switching from mitochondrial respiration to glycolysis by targeting PDK4 in unexplained recurrentspontaneousabortion. Studies have shown that EMT (epithelial-mesenchymal transition) and energy metabolism influence each other, and it is unclear whether the trophoblast energy metabolism phenotype
Analysis of gene expression difference and biological process in chorionic villi of unexplained recurrentspontaneousabortion. To explore the biological relationship between the regulatory signal pathways involved in differentially expressed genes and recurrentspontaneousabortion (RSA) by analyzing the gene expression microarray data of unexplained RSA. The gene expression profile data
Analysis of the implementation value of abdominal B-ultrasound combined with cervical cerclage in the prevention and treatment of late recurrentspontaneousabortion. To study the implementation value of abdominal B-ultrasound combined with cervical cerclage in the prevention and treatment of recurrent late abortion. From October 2020 to December 2023, 196 pregnant patients who had a history reduces the risk of miscarriage by improving the hemodynamic status of the uterus and placenta, and also optimizes the pregnancy environment by reducing the inflammatory response in the uterine cavity, which has important clinical applications in the prevention and treatment of late recurrentspontaneousabortion.
AMPK-mTOR pathway modulates glycolysis reprogramming in unexplained recurrentspontaneousabortion. Recurrentspontaneousabortion (RSA), whose underlying cause has yet to be fully elucidated, is often classified as unexplained recurrentspontaneousabortion (URSA). Promoting the differentiation of CD4 T cells into Tregs may be the key to prevent URSA. The differentiation of CD4 T cells
Miscarriage - Scenario: Recurrentmiscarriage Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential miscarriage?For women with recurrentmiscarriage (three or more first-trimester miscarriages):Offer referral for investigation and management. Advise that it may not be possible to determine the cause of recurrent miscarriage.If no cause is found, the prognosis for a successful future pregnancy with supportive care alone is about 75%. However, the prognosis worsens with increasing maternal age
Tacrolimus improved the pregnancy outcomes of patients with refractory recurrentspontaneousabortion and immune bias disorders: a randomized controlled trial. To investigate the effect of tacrolimus treatment on refractory recurrentspontaneousabortion (RSA) patients with elevated serum IL-33/ST2 levels. This study was a randomized controlled trial (RCT) of refractory RSA patients
Retracted: Clinical Impact of Nurses-Physicians Collaboration Intervention on the Treatment of Immune RecurrentSpontaneousAbortion with Low-Molecular-Weight Heparin. [This retracts the article DOI: 10.1155/2021/9290720.].
Clinical Research into Treating Unexplained RecurrentSpontaneousAbortion during Early Pregnancy with the Qing Yi Tiao Mian Formula. The present study aims to analyze the clinical effect of the Qing Yi Tiao Mian (QYTM) formula on unexplained recurrentspontaneousabortion (URSA) during early pregnancy and the immune balance of T lymphocytes. With their consent, 45 patients with URSA in weeks 4
Metastasis-associated lung adenocarcinoma transcript 1 induces methyl-CpG-binding domain protein 4 in mice with recurrentspontaneousabortion caused by anti-phospholipid antibody positivity. Antiphospholipid syndrome is an autoimmune disease characterized by pregnancy-related morbidity, related to persistent positivity of antiphospholipid antibodies (APL). One of the characteristics of pregnancy-related morbidity in patients with antiphospholipid syndrome is recurrentspontaneousabortion (RSA). This study aimed to examine the mechanism through which metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) regulates methyl-CpG-binding domain protein 4 (MBD4) expression in APL-positive RSA. Clinical samples were subjected to microarray analysis to filter differentially expressed
Role of kisspeptin in decidualization and unexplained recurrentspontaneousabortion via the ERK1/2 signalling pathway. This study aimed to study the expression and function of kisspeptin during human uterine decidualization in recurrentspontaneousabortion (RSA) and the underlying mechanism. All patients were recruited from the Clinical Reproductive Center of the Second Affiliated Hospital
Jiawei Shoutai Pill promotes decidualization by regulating the SGK1/ENaC pathway in recurrentspontaneousabortion. Jiawei Shoutai Pill (JWSTW) is a traditional herbal formula for recurrentspontaneousabortion (RSA). Although JWSTW significantly improves the clinical symptoms of RSA patients, its molecular mechanism remains unclear. This study evaluated the expression and function of the serum
Uncovering the pharmacological mechanism of Shou Tai Wan on recurrentspontaneousabortion: A integrated pharmacology strategy-based research. Shou Tai Wan (STW), a traditional Chinese medicine formula, has been historically used for the treatment of recurrentspontaneousabortion (RSA). Despite its long-standing usage, the exact mechanism underlying the therapeutic effects of STW remains
Retracted: Influence of Bushen Tiaochong Cycle Therapy on Th1/Th2 Deviation, Sex Hormone Level, and Pregnancy Outcome of Alloimmune RecurrentSpontaneousAbortion. [This retracts the article DOI: 10.1155/2021/8624414.].
Amelioration of intestinal barrier function and reduction of blood lead level in adult women with recurrentspontaneousabortion by a novel product of dietary fiber mixture, Holofood. The elevated circulating toxins secondary to the impairment of intestinal barrier integrity commonly elicit a chronic inflammatory response and finally contribute to multiple diseases. These toxins, including bacterial by-products and heavy metals, are the potent risk factors for the development of recurrentspontaneousabortion (RSA). Preclinical evidence suggests that several dietary fibers can restore intestinal barrier function and decrease the accumulation of heavy metals. However, it is uncertain whether treatment with a newly developed blend of dietary fibers product (Holofood) benefits patients