ScleremaNeonatorum in a Full-Term Infant Showing Favorable Prognosis Scleremaneonatorum (SN) is a rare disease characterized by firm, indurated, waxy skin lesions extending throughout the body, sparing the fat-free soles, palms, and genitalia. The prognosis of SN is generally very poor, with a high fatality rate. We report the case of a full-term infant with delayed onset of SN showing good
ScleremaNeonatorum Treated Successfully with Parenteral Steroids: An Experience from a Resource Poor Country Scleremaneonatorum is a form of panniculitides characterized by diffuse hardening of subcutaneous tissue with minimal inflammation. It usually affects ill and preterm neonates. Prognosis is usually poor in many cases despite aggressive management. Various treatment modalities (antibiotics, intravenous immunoglobulin, steroids, and exchange transfusion) have been explained in literature. Steroids due to its easy availability and low cost can prove to be lifesaving in such cases, especially in resource poor countries. Here, we report a case of scleremaneonatorum in a one-week preterm baby treated successfully with parenteral steroids and antibiotics.
[Effects of Ligustrazine Injection on Serum Cys C Level in Scierema Neonatorum Children Patients]. Objective To observe the effects of Ligustrazine Injection (LI) on serum cystatin C (Cys C) level in scleremaneonatorum (SN) children patients. Methods Totally 69 SN children patients were recrui- ted as the SN group, 39 with mild SN and 30 with moderate-severe SN. Another 30 neonates were
Newborn With Enlarged Erythematous Mass on Back: Case Report and Review of Medical Literature Newborn skin nodules are usually benign and self-resolving skin condition. Differential diagnosis of such lesions include cysts, hemangioma, abscess, cellulitis, scleremaneonatorum, subcutaneous fat necrosis, neurofibromatosis, benign tumors, or malignant tumors such as rhabdomyosarcoma, infantile
exposure. In infants, the cheeks and forehead are areas that may be affected.Cold panniculitis needs to be distinguished from other disorders such as adiponecrosis subcutanea (subcutaneous fat necrosis of the newborn, cold panniculitis of the newborn) and scleremaneonatorum. [4] Some overlap occurs, and cold panniculitis of the newborn has been associated with ice pack application. [5] In cold panniculitis of the newborn (adiponecrosis subcutanea), cold injury in the full-term newborn may occur with focal fat necrosis and a granulomatous and fibrous panniculitis in which the infiltrate usually contains multifocal histiocyte foreign body giant cells containing bifringent star-shaped crystals. [6] In scleremaneonatorum, a usually fatal disorder of infants who are premature or debilitated
exposure. In infants, the cheeks and forehead are areas that may be affected.Cold panniculitis needs to be distinguished from other disorders such as adiponecrosis subcutanea (subcutaneous fat necrosis of the newborn, cold panniculitis of the newborn) and scleremaneonatorum. [4] Some overlap occurs, and cold panniculitis of the newborn has been associated with ice pack application. [5] In cold panniculitis of the newborn (adiponecrosis subcutanea), cold injury in the full-term newborn may occur with focal fat necrosis and a granulomatous and fibrous panniculitis in which the infiltrate usually contains multifocal histiocyte foreign body giant cells containing bifringent star-shaped crystals. [6] In scleremaneonatorum, a usually fatal disorder of infants who are premature or debilitated