"Silent stroke"

Silent Cerebral Events/Lesions after Second-generation Cryoballoon Ablation ∼ How can we reduce the risk of silent strokes? ∼. Atrial fibrillation (AF) ablation is associated with a substantial risk of silent cerebral events/lesions (SCEs/SCLs) detected on magnetic resonance imaging (MRI). The purpose of this study was to investigate the factors associated with the incidence of SCEs/SCLs during

Impact of periprocedural anticoagulation therapy on the incidence of silent stroke after atrial fibrillation ablation in patients receiving direct oral anticoagulants: uninterrupted vs. interrupted by one dose strategy. Data on the comparison between uninterrupted and interrupted by one dose strategies for direct oral anticoagulant (DOAC) use during the periprocedural period of atrial fibrillation (AF) ablation are scarce. The purpose of this study is to investigate the feasibility of uninterrupted DOAC strategy by evaluating the incidence of silent stroke (SS) and perioperative trends in coagulation markers compared with the interrupted strategy. We randomly divided 200 consecutive patients receiving DOACs, who underwent AF ablation into uninterrupted group (UG = 100) and interrupted

Reduction in overt and silent stroke recurrence rate following cerebral revascularization surgery in children with sickle cell disease and severe cerebral vasculopathy Children with sickle cell disease (SCD) and moyamoya may benefit from indirect cerebral revascularization surgery in addition to chronic blood transfusion therapy for infarct prevention. We sought to compare overt and silent

Atrial fibrillation and silent stroke: links, risks, and challenges Atrial fibrillation (AF) is the most common cardiac arrhythmia, with a projected number of 1 million affected subjects in Germany. Changes in age structure of the Western population allow for the assumption that the number of concerned people is going to be doubled, maybe tripled, by the year 2050. Large epidemiological technology simplifies diagnostic procedures of these lesions and leads to a large amount of diagnosed lesions, but there is still no final conclusion about frequency, risk factors, and clinical relevance of these infarctions. The prevalence of silent strokes in patients with AF is higher compared to patients without AF, and several studies reported high incidence rates of silent strokes after AF ablation

Diagnostic Approach of Early Atrial Fibrillation, Silent Stroke and Cognitive Disorder in Patients With High-risk The goal of this observational study is to determine the impact of the combined use of cardiac rhythm recording devices, biomarkers, echocardiogram, and Magnetic Resonance Imaging (MRI) on the early detection of AF, silent stroke, and cognitive impairment in subjects older than 65 evaluation through an echocardiogram (to detect atrial dysfunction), cranial MRI (to detect silent strokes), plasma/serum collection to determine biomarkers, and a complete clinical assessment (including electrocardiogram, and scales for measurement of cognitive and functional status). The clinical evaluation will be repeated every 6 months and will allow the recording of the date of occurrence

Investigating silent strokes in hypertensives: a magnetic resonance imaging study (ISSYS): rationale and protocol design. Silent brain infarcts are detected by neuroimaging in up to 20% of asymptomatic patients based on population studies. They are five times more frequent than stroke in general population, and increase significantly both with advancing age and hypertension. Moreover , they are independently associated with the risk of future stroke and cognitive decline.Despite these numbers and the clinical consequences of silent brain infarcts, their prevalence in Mediterranean populations is not well known and their role as predictors of future cerebrovascular and cardiovascular events in hypertensive remains to be determined.ISSYS (Investigating Silent Strokes in Hypertensives: a magnetic

TransCranial Doppler for REDUCtion of Silent strokE During MitraClip Implantation The primary goal of the TCD-REDUCE study is to demonstrate the effectiveness of continuous transcranial Doppler sonography ("sonolysis") on the reduction of the ischemic stroke volume during MitraClip implantation. Cardiac procedures are associated with new cerebral ischemic lesions detected on diffusion-weighted

, and sleep apnoea or pulmonary disease. Causes significant morbidity (e.g., palpitations, dyspnoea, angina, dizziness or syncope, and features of heart failure, tachycardia-induced cardiomyopathy, or stroke) and death. Many patients are asymptomatic or have symptoms that are less specific for cardiac arrhythmias, such as mild dementia or silent strokes. ECG shows absent P waves, presence of fibrillatory

performing “extended red cell antigen profile by genotype or serology over only ABO/RhD typing for all patients with SCD (all genotypes) at the earliest opportunity (optimally before the first transfusion)” (Chou et al. 2020)5. Stroke, silent cerebral infarcts (silent strokes), and cognitive morbidity are the most common permanent sequelae of SCD in children and adults, occurring in approximately 39

(all genotypes) at the earliest opportunity (optimally before the first transfusion)”6. Stroke, silent cerebral infarcts (silent strokes), and cognitive morbidity are the most common permanent sequelae of SCD in children and adults. Consequent to this risk for adverse neurodevelopmental outcome, children aged 2-16 years should have annual transcranial doppler (TCD) performed to assess risk

, education, training, and advocacy in hematology.SCD-Related Cerebrovascular DiseaseWhat it coversWhy it mattersWho it affects• Screening and treatment guidelines for SCD complications affecting the brain, including risk of strokes and other neurological complications for both children and adults.• Neurologic complications such as stroke and silent stroke are a major cause of disability and death for children and adults living with SCD. • Effective screening for stroke risk in SCD may help prevent or reduce the risks associated with these types of complications.• “Silent strokes” – those without obvious neurological symptoms – affect 1 in 3 children and at least 1 in 2 adults with SCD, and often go undetected. They are linked to cognitive impairment potentially impacting school performance

, screening, thalassemia, blood transfusion, cerebrovascular accident, cognitive impairment, sickle cell anemia, silent stroke RED CELLS, Anemia-Clinical: Sickle cell anemia Summary of recommendationsBackgroundStroke, silent cerebral infarcts (silent strokes), and cognitive morbidity are the most common permanent sequelae of sickle cell disease (SCD) in children and adults. Prior to 1990 in the United

includes arterial ischemic stroke (AIS) and venous infarction caused by cerebral sinovenous thrombosis (CSVT) or cortical vein thrombosis. In CSVT, occlusion of venous sinuses may or may not be accompanied by hemorrhage. In older infants and children, some literature uses the term silent stroke when asymptomatic infarcts are found on neuroimaging. However, this is a misnomer because the definition

Memory after silent stroke: Hippocampus and infarcts both matter. Memory decline commonly occurs among elderly individuals. This observation is often attributed to early neurodegenerative changes in the hippocampus and related brain regions. However, the contribution of vascular lesions, such as brain infarcts, to hippocampal integrity and age-associated memory decline remains unclear. We

Silent Stroke: Not Listened to Rather Than Silent. The prevalence of silent brain infarcts varies from 8% to 28% in the general elderly population. Silent brain infarcts are associated with increased risk of subsequent stroke and cognitive dysfunction. By definition, silent strokes lack clinically overt stroke-like symptoms and fail to come to clinical attention; however, impaired recall -weighted imaging with corresponding apparent diffusion coefficient defects indicative of acute/subacute silent stroke were identified. Clinical data for individuals with incidental hyperintense lesions on diffusion-weighted imaging were collated. Six of 649 subjects had incidental hyperintense lesions on diffusion-weighted imaging; on retrospective questioning, 3 recalled symptoms temporally correlated