"Skin grafting"

Syndactyly release with skin graft or skin graft substitute: a within-subject controlled trial. This study assessed scar healing over a 24-month period after syndactyly release using full-thickness skin autograft or hyaluronic acid matrix skin autograft substitute. A randomized, single-anonymized, within-subject controlled study was used to compare the effectiveness of hyaluronic acid matrix

Skin graft management for burn patients NSW Statewide Burn Injury ServiceSkin graft management for burn patients A clinical guideOCTOBER 2020aci.health.nsw.gov.auThe information is not a substitute for healthcare providers’ professional judgement.Agency for Clinical Innovation1 Reserve Road St Leonards NSW 2065 Locked Bag 2030, St Leonards NSW 1590 T +61 2 9464 4666 | F +61 2 9464 4728 E aci purposes subject to the inclusion of an acknowledgment of the source. It may not be reproduced for commercial usage or sale. Reproduction for purposes other than those indicated above, requires written permission from the Agency for Clinical Innovation. Preferred citation: NSW Agency for Clinical Innovation. Skin graft management for burns patients – A clincial guide.SHPN (ACI) 200184 I S B N 978‑1‑76 0

Biomechanical and aesthetic outcomes following radial forearm free flap transfer: comparison of ipsilateral full-thickness skin graft and traditional split-thickness skin graft. The radial forearm free flap (RFFF) is associated with donor site morbidity. This study aimed to quantify the functional and aesthetic outcomes after closure of the RFFF donor site using triangular full-thickness skin grafts (FTSGs) harvested adjacent to the flap or traditional split-thickness skin grafts (STSGs). The study included patients who underwent oral cavity reconstruction with an RFFF between March 2017 and August 2021. The patients were divided into two groups based on the donor site closure method: FTSG or STSG. The primary outcomes were biomechanical grip strength, pinch strength, and range of wrist

Short-term morbidity following primary closure, skin grafting and flap reconstruction after surgical resection of extremity soft-tissue sarcomas: Pushing the limits of limb preservation. Understanding short-term morbidity following extremity soft-tissue sarcoma (ESTS) treatment remains complex due to diverse findings and the absence of a standardized wound complication assessment . This retrospective cohort study evaluated short-term morbidity following primary closure, skin grafting, and flap reconstruction. All ESTS patients treated in a sarcoma center in the Netherlands from 1-1-2010 until 1-8-2022 were included. Short-term morbidity, defined as a wound complication following surgery, was assessed by the Toronto Sarcoma Flap Score (TSFS). The TSFS is an ordinal scale, where 0 indicates

Investigating the Impact of Wound Edge Approximation With Skin Grafting on Hypertrophic Scar Reduction: A Randomized Controlled Clinical Trial. In modern burn care, the focus extends beyond mere patient survival to encompass long-term functional and cosmetic outcomes. Research suggests that the technique and manner of suturing during skin grafting play a significant role in scar formation . This study aimed to explore the effectiveness of wound edge approximation with skin grafting compared to the conventional approach, where the graft edge exclusively interacts with the wound edge, in reducing hypertrophic scar development. Seventy-four burn unit patients eligible for grafting were randomly allocated into 2 groups: those receiving grafts with overlapping edges (Group A) and those receiving

Effectiveness of a Regenerative Epithelial Suspension (RES), on the pigmentation of split-thickness skin graft donor sites in children: the dRESsing pilot randomised controlled trial protocol. Paediatric donor site wounds are often complicated by dyspigmentation following a split-thickness skin graft. These easily identifiable scars can potentially never return to normal pigmentation . All children aged 16 years or younger requiring a split thickness skin graft will be screened for eligibility. The primary outcome is donor site scar pigmentation 12 months after skin grafting. Secondary outcomes include re-epithelialisation time, pain, itch, dressing application ease, treatment satisfaction, scar thickness and health-related quality of life. Commencing 7 days after the skin graft

Efficacy of platelet-rich plasma in alleviating split skin graft morbidities. Skin grafting is a routinely employed technique to cover the skin defect. Though the skin grafts are technically effortless, they are tiresome because of the prolonged duration of hospital stay, labor-intensive, demanding repeated dressings, and also create a second wound. Platelet-rich plasma (PRP) is one that has a higher concentration of platelets than the blood. Alpha granules of the platelets are rich in growth factors. To assess the effect of PRP on split-thickness skin graft uptake and donor site healing. In a single-center-based prospective study done from August 2018 to June 2020, 60 patients with acute and chronic wounds were divided into two equal groups. Autologous PRP was applied on the recipient wound

Randomized comparative study of negative pressure wound therapy versus compression dressing on split-thickness skin grafts of the lower limbs in an elderly population. Failure to adequately secure the skin graft to the lower limbs recipient bed can result in loss of the graft. Our objective was to compare the healing of split-thickness skin grafts three weeks postoperatively, using either negative pressure wound therapy (NPWT) or conventional compression bandaging. In this multicenter randomized controlled study, patients with tissue loss ranging from 50 cm to 600 cm on the lower limbs and treated with split-thickness skin grafts were included in three French hospitals. A digital photographic evaluation was performed at 3 weeks. During 9 years, 70 patients were included in the study

Evaluating the association between time to skin grafting for truncal burn patients and complications: a comparative cohort study using the National Trauma Data Bank.

Clinical study on the role of platelet-rich plasma in human acellular dermal matrix with razor autologous skin graft repair of giant congenital pigmented nevus in children. NA OBJECTIVE: Evaluate the safety and feasibility of platelet-rich plasma (PRP) in the treatment of giant congenital melanocytic nevi (GCMN) in children with human acellular dermal matrix (HADM) transplantation. A total of 22 children with GCMN were included in the study. They were divided into an experimental and a control group. The experimental group used the method of HADM with Razor Autologous Skin Graft combined with PRP to repair skin and soft tissue defects after giant nevus resection (Group A, n = 11). The control group was treated with HADM with Razor Autologous Skin Graft (Group B, n = 11) only. To compare

Pedicled flap versus skin graft for great toe defect repair after wrap-around flap transfer. This study compared the clinical outcomes of tibial-sided digital artery pedicled flap from the second toe versus full-thickness skin grafting to repair great toe defects after wrap-around flap transfers. The pedicled flap resulted in better pain scores and aesthetic outcomes.

Outcomes of Radial Forearm Free Flap Closure With Split-Thickness Skin Graft Versus Primary Closure. This study compares patient-reported functional and aesthetic outcomes of split-thickness skin graft (STSG) versus hatchet flap closure of radial forearm free flap (RFFF) donor site. Patients with RFFF (2015-2020) were retrospectively identified. Those willing to participate in patient-reported

Skin graft surgery and its impact on platelet counts in Iranian burn patients: a non-randomized clinical trial. Platelets are critical in maintaining homeostasis and immune response in burn patients. The concentration of platelets decreases in burn patients, and any intervention that increases serum platelet concentration can prevent serious consequences and patient death. The present study aimed to assess the impact of skin graft surgery on burn patients' platelet counts. In this non-randomized clinical trial, 200 burn patients were investigated. The patients were recruited from the surgical ward of Imam Khomeini Teaching Hospital during the first six months of 2021. After completing the checklist, patients underwent skin graft surgery. Blood was taken from the patients during surgery

Comparative Analysis of Autologous Skin Cell-suspension Technology and Split-thickness Skin Grafting for Subacute Wounds in Medically Complex Patients: Propensity-Matched Cohort Study. Non-healing wounds are particularly prevalent in older adults and in patients with multiple comorbidities and represent a significant medico-economic burden. Autologous split-thickness skin grafts (STSG

Intact Fish Skin Graft to Treat Deep Diabetic Foot Ulcers. Diabetic foot ulcers are chronic, difficult to heal, and potentially life-threatening. Few medical devices have been studied in diabetic ulcers penetrating to bone or tendon. We conducted an international, open-label randomized controlled trial, randomly assigning patients with diabetic ulcers penetrating to bone, joint, or tendon 1:1 to intact fish skin graft or standard wound care, with assigned treatment applied through 14 weeks. The primary end point was the proportion of ulcers healed at 16 weeks, defined as reepithelization as identified by the investigator, and confirmed 14 days later. A blinded adjudication committee confirmed healing at both time points. Healing was also assessed at 20 and 24 weeks. Between July 2020

Investigating the outcomes of full thickness skin graft in the reconstruction of concealed penis in children aged 7 to 14 years. Concealed penis is a congenital anomaly that affects not only the appearance but also the function of the external genitalia in the male sex. Different surgical methods have been proposed to correct this disorder, including removal of the previous scar, penile shaft , penile trunk skin reconstruction with flap, penile skin fixation in penopubic and penoscrotal angles, and removal of extra pubic fat. In this study, we will discuss the results of definitive surgery in one stage using autogenous skin grafts and examine the details of this technique. This study was conducted as a clinical trial in Hospitals related to the Isfahan University of Medical Sciences. Children

Characterizing the use of full- and split-thickness skin grafts among dermatologists: an international survey. The use of full-thickness and split-thickness skin grafts (FTSG/STSG) among dermatologists has not been well characterized. To characterize the utilization of graft techniques, fixation methods and training needs pertaining to graft use among an international cohort of dermatologists ; and 30.0% (45 of 150) did not undertake skin grafts in their practice. Of the 67 Mohs surgeons, only 42% (28 of 67) undertook both FTSG and STSG. Overall, common donor sites for FTSG included the preauricular area (86 of 105; 81.9%) and clavicle (75 of 105; 71.4%), while the thigh was the most common donor site for STSG (30 of 35; 86%). Grafts were fixed mostly with sponge tie-over dressings and basting

Single-Stage Reconstruction of Large Scalp Surgical Defects With Exposed Bone Using Matriderm Flex and Full-Thickness Skin Grafts, a Case Report. The reconstruction of full-thickness scalp defects with exposed bone can be challenging. A single-stage reconstruction could be the preferred option for patients with multiple comorbidities. We propose using a dermal regeneration template (Matriderm Flex) and full-thickness skin grafts. The approach shown in this case report allows for quick healing, less donor-site discomfort in comparison with dermatome-harvested skin grafts, and very good aesthetic results, matching the surrounding skin thickness.

Surgical Treatment for Chest "Lock" Keloid Using Autologous Split-Thickness Skin Grafting and Postoperative Radiotherapy. The treatment of chest "lock" keloids is challenging due to skin defects and a high recurrence rate. Evaluation of the effectiveness of autologous split-thickness skin graft with local radiotherapy for treating chest "lock" keloids. Fifty-seven patients with chest "lock " keloids were treated from July 2018 to September 2020. The skin defects were closed with an autologous split-thickness skin graft (STSG) and vacuum sealing drainage. The donor and the recipient sites received the first session of radiotherapy 72 hours postoperation for 3 consecutive days. Patients underwent follow-up examinations 12 months after surgery. The Patient and Observer Scar Assessment Scale

Reduced time to skin grafting in chronic wounds using an esterified hyaluronic acid matrix and negative pressure wound therapy. The use of NPWT and eHAM can aid in the closure of chronic wounds with exposed bone and tendon. The authors examined the time to skin grafting and wound closure in 10 patients after treatment with either NPWT with eHAM (group 1, n = 5) or NPWT without eHAM (group 2, n = 5). The average time to closure was similar between group 1 and group 2 (15.2 weeks vs 14.6 weeks) despite a nearly twofold greater initial wound area. However, the rate of wound closure per week was better in group 1 than in group 2 in terms of both area (9.0 cm2 vs 6.8 cm2) and volume (12.3 cm3 vs 5.4 cm3). In addition, the rate of wound closure per week at skin grafting was better in group 1