"Small-cell carcinoma"

36,569 resultsPro users have access to +5169 Systematic Reviews

Filter Results
          • Pro
          • Pro
          • Pro
          • Pro
          • Pro
          • Pro
                    • Pro

                            Clinical Area Pro

                            Further Refinement
                            User Guide

                            User Guide

                            1
                            Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer Technology appraisal guidance Published: 19 February 2025 www.nice.org.uk/guidance/ta1042 © NICE 2025. All rights reserved. Subject to Notice of rights ( responsibility The recommendations in this guidance is recommended as an option for treating RET fusion-positive advanced non-small-cell lung cancer (NSCLC) that has not been treated with a RET inhibitor in adults, only if: • it has been treated before and • the company provides selpercatinib according to the commercial arrangement. 1.2 This recommendation is not intended to affect treatment with selpercatinib that was started in the NHS before this guidance
                            2
                            Durvalumab with etoposide and either carboplatin or cisplatin for untreated extensive-stage small-cell lung cancer Durvalumab with etoposide and either carboplatin or cisplatin for untreated extensive-stage small-cell lung cancer Technology appraisal guidance Published: 19 February 2025 www.nice.org.uk/guidance/ta1041 © NICE 2025. All rights reserved. Subject to Notice of rights ( responsibility of opportunity and to reduce health inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Durvalumab with etoposide and either carboplatin or cisplatin for untreated extensive-stage small-cell lung cancer (TA1041)© NICE 2025
                            Subscribe to Trip PRO for an enhanced experience
                            • Access to millions of Full-text articles where avaliable
                            • Unlock 100,000+ extra articles with Systematic Reviews
                            • Further Filtering Options
                            • No adverts
                            • Advanced Search Ability
                            • Enhanced SmartSearch showing unlimited related articles
                            Read more about Trip PRO
                            3
                            Osimertinib for adjuvant treatment of EGFR mutation-positive non-small-cell lung cancer after complete tumour resection Osimertinib for adjuvant treatment of EGFR mutation-positive non-small-cell lung cancer after complete tumour resection Technology appraisal guidance Published: 26 February 2025 www.nice.org.uk/guidance/ta1043 © NICE 2025. All rights reserved. Subject to Notice of rights Osimertinib is recommended, within its marketing authorisation, as an option for the adjuvant treatment of stage 1b to 3a non-small-cell lung cancer (NSCLC) after complete tumour resection. It is for adults whose tumours have epidermal growth factor receptor (EGFR) exon 19 deletions or EGFR exon 21 (L858R) substitution mutations. It is only recommended if: • osimertinib is stopped at 3 years, or earlier
                            4
                            Atezolizumab for untreated advanced or recurrent non-small-cell lung cancer when platinum-doublet chemotherapy is unsuitable (terminated appraisal) Atezolizumab for untreated advanced or recurrent non-small-cell lung cancer when platinum-doublet chemotherapy is unsuitable (terminated appraisal) Technology appraisal guidance Published: 12 March 2025 www.nice.org.uk/guidance/ta1047 © NICE 2025 cancer whenplatinum-doublet chemotherapy is unsuitable (terminated appraisal) (TA1047)© NICE 2025. All rights reserved. Subject to Notice of rights ( 2of 3 Advice NICE is unable to make a recommendation about the use in the NHS of atezolizumab for untreated advanced or recurrent non-small-cell lung cancer when platinum-doublet chemotherapy is unsuitable in adults. This is because Roche Products has
                            5
                            Pembrolizumab with chemotherapy before surgery (neoadjuvant) then alone after surgery (adjuvant) for treating resectable non-small-cell lung cancer Pembrolizumab with chemotherapy before surgery (neoadjuvant) then alone after surgery (adjuvant) for treating resectable non-small-cell lung cancer Technology appraisal guidance Published: 20 November 2024 www.nice.org.uk/guidance/ta1017 © NICE 2024 (neoadjuvant) then alone after surgery(adjuvant) for treating resectable non-small-cell lung cancer (TA1017)© NICE 2024. All rights reserved. Subject to Notice of rights ( 2 of25 Contents 1 Recommendations .................................................................................................................4 2 Information about pembrolizumab
                            6
                            Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer Technology appraisal guidance Published: 4 December 2024 www.nice.org.uk/guidance/ta1021 © NICE 2024. All rights reserved. Subject to Notice of rights ( responsibility The recommendations in this guidance represent the view of NICE, arrived at after . Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer (TA1021)© NICE 2024. All rights reserved. Subject to Notice of rights ( 2of 9 Contents 1 Recommendations
                            7
                            Pembrolizumab for adjuvant treatment of resected non-small-cell lung cancer Pembrolizumab for adjuvant treatment of resected non-small-cell lung cancer Technology appraisal guidance Published: 5 February 2025 www.nice.org.uk/guidance/ta1037 © NICE 2025. All rights reserved. Subject to Notice of rights ( responsibility The recommendations in this guidance represent the view of NICE, arrived inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Pembrolizumab for adjuvant treatment of resected non-small-cell lung cancer (TA1037)© NICE 2025. All rights reserved. Subject to Notice of rights ( 2 of29 Contents 1
                            8
                            Durvalumab with chemotherapy before surgery (neoadjuvant) then alone after surgery (adjuvant) for treating resectable non-small-cell lung cancer Durvalumab with chemotherapy before surgery (neoadjuvant) then alone after surgery (adjuvant) for treating resectable non-small-cell lung cancer Technology appraisal guidance Published: 15 January 2025 www.nice.org.uk/guidance/ta1030 © NICE 2025. All (neoadjuvant) then alone after surgery(adjuvant) for treating resectable non-small-cell lung cancer (TA1030)© NICE 2025. All rights reserved. Subject to Notice of rights ( 2 of29 Contents 1 Recommendation ...................................................................................................................4 2 Information about durvalumab
                            9
                            Trastuzumab deruxtecan for treating HER2-mutated advanced non-small-cell lung cancer after platinum-based chemotherapy (terminated appraisal) Trastuzumab deruxtecan for treating HER2-mutated advanced non-small-cell lung cancer after platinum-based chemotherapy (terminated appraisal) Technology appraisal guidance Published: 29 May 2024 www.nice.org.uk/guidance/ta976 © NICE 2024. All rights cancerafter platinum-based chemotherapy (terminated appraisal) (TA976)© NICE 2024. All rights reserved. Subject to Notice of rights ( 2of 3 Advice NICE is unable to make a recommendation about the use in the NHS of trastuzumab deruxtecan for treating HER2-mutated advanced non-small-cell lung cancer in adults who need systemic treatment after platinum-based chemotherapy with or without immunotherapy
                            10
                            Alectinib for adjuvant treatment of ALK-positive non-small-cell lung cancer Alectinib for adjuvant treatment of ALK-positive non-small-cell lung cancer Technology appraisal guidance Published: 13 November 2024 www.nice.org.uk/guidance/ta1014 © NICE 2024. All rights reserved. Subject to Notice of rights ( responsibility The recommendations in this guidance represent the view of NICE, arrived inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Alectinib for adjuvant treatment of ALK-positive non-small-cell lung cancer (TA1014)© NICE 2024. All rights reserved. Subject to Notice of rights ( 2of 7 Contents 1
                            11
                            2025Cochrane
                            Review Analysis
                            Appears Promising
                            ?
                            Prognosis of surgically resected clinical stage 1A non-small cell lung cancers manifesting as a subsolid nodule on computed tomography including pure ground glass nodules. This is a protocol for a Cochrane Review (prognosis). The objectives are as follows: To quantify the risk of tumour relapse/recurrence after a surgical resection of stage 1A non-small cell lung cancer (NSCLC) as manifested
                            12
                            2025FDA - Drug Approval Package
                            Zenocutuzumab zbco (Bizengri) - non-small cell lung cancer and pancreatic adenocarcinoma Drug Approval Package: BIZENGRI * Skip to main content * Skip to FDA Search * Skip to footer links An official website of the United States governmentHere's how you know The .gov means it's official.Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're
                            13
                            2025FDA - Drug Approval Package
                            Ensartinib (Ensacove) - non-small cell lung cancer Drug Approval Package: ENSACOVE * Skip to main content * Skip to FDA Search * Skip to footer links An official website of the United States governmentHere's how you know The .gov means it's official.Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site
                            14
                            Capmatinib for treating advanced non-small-cell lung cancer with MET exon 14 skipping (terminated appraisal) Capmatinib for treating advanced non-small-cell lung cancer with MET exon 14 skipping (terminated appraisal) Technology appraisal guidance Published: 3 May 2023 www.nice.org.uk/guidance/ta884 © NICE 2023. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms -and-conditions#notice-of-rights).Contents Advice ................................................................................................................................3 Information ..................................................................................................................................3 Capmatinib for treating advanced non-small-cell lung cancer with MET exon 14 skipping
                            15
                            Lorlatinib for untreated ALK-positive advanced non-small-cell lung cancer Lorlatinib for untreated ALK-positive advanced non-small-cell lung cancer Technology appraisal guidance Published: 12 July 2023 www.nice.org.uk/guidance/ta909 © NICE 2023. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Your responsibility The recommendations of opportunity and to reduce health inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Lorlatinib for untreated ALK-positive advanced non-small-cell lung cancer (TA909)© NICE 2023. All rights reserved. Subject to Notice
                            16
                            Amivantamab for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy Amivantamab for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy Technology appraisal guidance Published: 14 December 2022 www.nice.org.uk/guidance/ta850 © NICE 2022. All rights reserved . Amivantamab for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy (TA850)© NICE 2022. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Page 2 of26Contents 1 Recommendations
                            17
                            Selpercatinib for untreated RET fusion-positive advanced non-small-cell lung cancer Selpercatinib for untreated RET fusion-positive advanced non-small-cell lung cancer Technology appraisal guidance Published: 26 July 2023 www.nice.org.uk/guidance/ta911 © NICE 2023. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Your responsibility of opportunity and to reduce health inequalities. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Selpercatinib for untreated RET fusion-positive advanced non-small-cell lung cancer(TA911)© NICE 2023. All rights reserved. Subject
                            18
                            Mobocertinib for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy Mobocertinib for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy Technology appraisal guidance Published: 4 January 2023 www.nice.org.uk/guidance/ta855 © NICE 2023. All rights reserved . Mobocertinib for treating EGFR exon 20 insertion mutation-positive advanced non-small-cell lung cancer after platinum-based chemotherapy (TA855)© NICE 2023. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Page 2 of27Contents 1 Recommendations
                            19
                            Dabrafenib plus trametinib for treating BRAF V600 mutation-positive advanced non-small-cell lung cancer Dabrafenib plus trametinib for treating BRAF V600 mutation-positive advanced non-small-cell lung cancer Technology appraisal guidance Published: 14 June 2023 www.nice.org.uk/guidance/ta898 © NICE 2023. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms non-small-cell lung cancer (TA898)© NICE 2023. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Page 2 of23Contents 1 Recommendations .................................................................................................................4 2 Information about dabrafenib plus trametinib
                            20
                            2024Cochrane
                            Review Analysis
                            Appears Promising
                            ?
                            Therapeutic vaccines for advanced non-small cell lung cancer. New strategies in immunotherapy with specific antigens that trigger an anti-tumour immune response in people with lung cancer open the possibility of developing therapeutic vaccines aimed at boosting the adaptive immune response against cancer cells. To evaluate the effectiveness and safety of different types of therapeutic vaccines for people with advanced non-small cell lung cancer. We searched CENTRAL, MEDLINE, Embase, Wanfang Data, and China Journal Net (CNKI) up to 22 August 2023. We included parallel-group, randomised controlled trials evaluating a therapeutic cancer vaccine, alone or in combination with other treatments, in adults (> 18 years) with advanced non-small cell lung cancer (NSCLC), whatever the line of treatment. We