Tear film stability in patients with symptoms of dry eye after instillation of dual polymer hydroxypropyl guar/sodiumhyaluronate vs single polymer sodiumhyaluronate. This study evaluated the tear film stability in patients with symptoms of dry eye after installation of dual polymer hydroxypropyl guar/sodiumhyaluronate (DPHG/SH) vs single polymer SH. Patients with recently diagnosed mild
Reaction to Synvisc and approach for other sodiumhyaluronate agents Cookie NoticeThis site uses cookies. By continuing to browse this site, you are agreeing to our use of cookies. Review our cookies information for more details.OKskip to main contentToggle site navigationAllergist Resources Ask The Expert 2023 Reaction To Synvisc And Approach For Other SodiumHyaluronate AgentsReaction to Synvisc and approach for other sodiumhyaluronate agentsQuestion:12/22/2023I have a patient who needs an eye surgery in which a hylan/viscoelastic product will be injected and then pulled out. She had reaction after her third intra-articular Synvisc injection (approx. 2015) in which he next day her knee was red, swollen, could not put pressure on. She reportedly needed to have Synvisc removed
Effect of laughter exercise versus 0.1% sodiumhyaluronic acid on ocular surface discomfort in dry eye disease: non-inferiority randomised controlled trial. To assess efficacy and safety of laughter exercise in patients with symptomatic dry eye disease. Non-inferiority randomised controlled trial. Recruitment was from clinics and community and the trial took place at Zhongshan Ophthalmic Center , Sun Yat-sen University, the largest ophthalmic centre in China, between 18 June 2020 to 8 January 2021. People with symptomatic dry eye disease aged 18-45 years with ocular surface disease index scores ranging from 18 to 80 and tear film break-up time of eight seconds or less. Participants were randomised 1:1 to receive laughter exercise or artificial tears (0.1% sodiumhyaluronic acid eyedrop
Comparative efficacy of 0.1% and 0.15% SodiumHyaluronate on lipid layer and meibomian glands following cataract surgery: A randomized prospective study. To compare the efficacy of a 0.15% HA with that of 0.1% HA eye drops for DES after cataract surgery. This study was double blinded, randomized and prospective study, and conducted in 69 participants (70 eyes) from Pusan National University
Sodiumhyaluronate 0.30% ocular gel versus sodiumhyaluronate 0.18% eye drop in the treatment of moderate to severe dry eye disease. Compare 0.30% sodiumhyaluronate (0.30%HA) ocular gel with 0.18%HA eye drops in terms of improvement of ocular signs and symptoms, in patients with moderate to severe dry eye disease (DED). This was a multicentric, randomized, investigator-masked, non-inferiority
Clinical Study of Intradermal Injection of Non-Crosslinked SodiumHyaluronate Combined With Human Epidermal Growth Factor in the Treatment of Skin Barrier Injury in Plateau Area. The Yunnan-Guizhou Plateau's high-altitude setting is characterized by intense solar ultraviolet radiation, a significant environmental stressor that frequently leads to skin barrier damage. This damage presents
Comparison of polynucleotide, sodiumhyaluronate, and crosslinked sodiumhyaluronate for the management of painful knee osteoarthritis: a multi-center, randomized, double-blind, parallel-group study. To compare the clinical effectiveness of sodium polynucleotide, classic hyaluronic acid, and crosslinked hyaluronic acid for the management of painful knee osteoarthritis. Randomized, double-blind
Preventive effects of sodiumhyaluronate combined with pelvic floor neuromuscular electrical stimulation on the intrauterine adhesions in women after abortion. The aim of this study was to investigate the clinical efficacy of combining pelvic floor neuromuscular stimulation treatment (NMES) with sodiumhyaluronate in preventing intrauterine adhesions (IUA) following abortion. A total of 140 women who underwent artificial abortion were enrolled. The control group received only an intrauterine injection of sodiumhyaluronate post-surgery, while the observation group received both the injection and daily pelvic floor NMES treatments, beginning on the day after the abortion. Monthly follow-ups on menstrual conditions were conducted for six months post-surgery. Fasting venous blood samples from
Efficacy of an experimental toothpaste containing sodium bicarbonate, sodiumhyaluronate and sodium fluoride on gingivitis. Gingivitis is driven by plaque accumulation and, if left untreated, can progress to irreversible periodontitis. For many, the mechanical action of toothbrushing does not achieve adequate plaque control. The aim of this study was to investigate whether twice-daily use of a toothpaste containing 0.2% high molecular weight (HMW) sodiumhyaluronate with 67% sodium bicarbonate and 0.221% sodium fluoride (experimental toothpaste) could improve gingival health compared with a regular fluoride toothpaste (negative control). The study also assessed whether the experimental toothpaste could provide additive gingival health benefit over a toothpaste containing only 67% sodium
Use of SodiumHyaluronate and Triamcinolone Acetonide Following Arthrocentesis in Treatment of Internal Derangement of Temporomandibular Joint: A Prospective Randomized Comparative Study. Internal derangement (ID) of temporomandibular joint (TMJ) is a common temporomandibular disorder (TMD) which causes hypomobility of the joint. Minimally invasive treatment modality like arthrocentesis is used as first-line of management having low morbidity and high efficacy. This prospective randomized comparative study was carried to compare the efficacy of intra-articular injection with sodiumhyaluronate (SH) and triamcinolone acetonide (TA) after arthrocentesis in ID of TMJ. A total 40 patients diagnosed with ID (stage 1-4) were included in the study and randomly divided in two groups. Twenty patients
Efficacy of topical 0.05% cyclosporine A and 0.1% sodiumhyaluronate in post-refractive surgery chronic dry eye patients with ocular pain. The management of post-refractive surgery dry eye disease (DED) can be challenging in clinical practice, and patients usually show an incomplete response to traditional artificial tears, especially when it is complicated with ocular pain. Therefore, we aim to investigate the efficacy of combined topical 0.05% cyclosporine A and 0.1% sodiumhyaluronate treatment in post-refractive surgery DED patients with ocular pain unresponsive to traditional artificial tears. We enrolled 30 patients with post-refractive surgery DED with ocular pain who were unresponsive to traditional artificial tears. Topical 0.05% cyclosporine A and 0.1% sodiumhyaluronate were used for 3
A Prospective, Randomized, Controlled Clinical Investigation Comparing the Efficacy and Safety of SodiumHyaluronate-Based Ophthalmical Viscosurgical Devices FIDIAL PLUS and IAL(®)-F in Cataract Surgery. To protect the corneal endothelium, various ophthalmical viscoelastic devices (OVDs) are used during cataract surgery. In this study, we compared two sodiumhyaluronate-based OVD, the bacteria
A randomized controlled clinical trial of concentrated growth factor combined with sodiumhyaluronate in the treatment of temporomandibular joint osteoarthritis. To investigate the effect of concentrated growth factor (CGF) combined with sodiumhyaluronate (SH) on temporomandibular joint osteoarthritis (TMJOA). Sixty patients with TMJOA who were diagnosed by cone-beam computed tomography (CBCT
Evaluating the Efficacy and Safety of Hemofence (Thorombin Cross-linked SodiumHyaluronate Gel Matrix) in Hemostasis for Intractable Exudative Bleeding in Spinal Surgery: A Multicenter, Randomized, Phase III Clinical Trial. To demonstrate the non-inferiority of the novel hemostatic agent, Hemofence® (BMI Korea Co. Ltd., Jeju Korea, thrombin cross-linked sodiumhyaluronate gel matrix) compared
Sodiumhyaluronate and pranoprofen improve visual function and reduce inflammation in patients with dry eye. The aim of this study was to investigate the clinical use of sodiumhyaluronate (SH) combined with pranoprofen in treating patients with dry eye. A total of 117 patients with dry eye who were treated in the Traditional Chinese Medicine Hospital of Kunshan from March 2020 and May 2022 were
Comparing the efficacy of sodiumhyaluronate eye drops and carboxymethylcellulose eye drops in treating mild to moderate dry eye disease. Aim of this study was to compare the efficacy of sodiumhyaluronate (SH) and carboxymethyl cellulose (CMC) eye drops in treating mild to moderate dry eye disease in terms of relief of symptoms, mean change in tear film breakup time, Schirmer's test
The Effect of SodiumHyaluronate Eye Drops 2, 4 or 6 Times a Day on Signs and Symptoms of Dry Eye Disease. A randomized clinical trial was run to evaluate the effectiveness of a preservative-free 0.4% sodiumhyaluronate eye drop (LOF) in different dosage schemes to alleviate signs and symptoms of dry eye disease (DED). A total of 116 subjects with mild-to-moderate DED were included, and 111
Repairing Effect and Mechanism of Hydroxysafflor Yellow A and SodiumHyaluronate for Knee Osteoarthritis in Rabbits. KOA characterized by recurrent joint pain and progressive joint dysfunction. Is the present clinical common chronic progressive degenerative osteoarthropathy, how long the disease is difficult to cure and easy to relapse. Exploring new therapeutic approaches and mechanisms is important for the treatment of KOA. One of the main applications for sodiumhyaluronate (SH) in the medical field is treatment of osteoarthritis. However, the effects of SH alone in the treatment of KOA are limited. Hydroxysafflor yellow A (HSYA) may have therapeutic effects for KOA. The study intended to investigate the therapeutic effects and possible mechanisms of action HSYA+SH for cartilage tissue
Diluting 2.5% Viscoadaptive SodiumHyaluronate to Prevent Postoperative Intraocular Pressure Rise After Phacoemulsification: A Pilot Study. The most common complication with intraoperative viscoelastic use is an immediate elevation of intraocular pressure, particularly if the viscoelastic agent remains in the eye, which can cause serious effects. Complications may include severe ocular pain , corneal epithelial edema, and increased risk of anterior ischemic optic neuropathy and retinal artery occlusion. This study aims to find an efficient and safe adjunctive method to decrease the incidence of postoperative intraocular pressure rise. When cohesive viscoelastic agents were unavailable due to the pandemic, we diluted Microvisc 2.5% sodiumhyaluronate ophthalmic viscosurgical device by 50
The effect of sodiumhyaluronate on tear film stability in patients with dry eye syndrome after cataract surgery. This study aimed to observe the changes in the ocular surface after phacoemulsification in patients with age-related cataracts with respect to the addition of varying concentrations of hyaluronate. Patients with dry eye syndrome were treated with 0.3% and 0.1% sodiumhyaluronate eye drops to evaluate the clinical improvement in each treatment group. A total of 73 patients (91 eyes) with age-related cataracts suffering from dry eye syndrome after phacoemulsification were divided into treatment group A (30 eyes), undergoing conventional therapy and treatment with 0.3% sodiumhyaluronate; treatment group B (31 eyes), undergoing conventional therapy and treatment with 0.1% sodium