Comparison of [(68)Ga]Ga-Fibroblast Activation Protein Inhibitor-04 and [(18)F]FDG PET Imaging for SolitaryFibrousTumor and Preliminary Application of FAP-Targeted Radiopharmaceutical Therapy. Solitaryfibroustumor (SFT) is a rare sarcoma of mesenchymal origin. Although generally benign, SFTs carry the risk of recurrence and metastasis, with limited effective treatment options. The aims
Laparoscopic Minimally Invasive Approach for Pelvic SolitaryFibrousTumor. A solitaryfibroustumor (SFT) is a rare mesenchymal fibroblastic tumor characterized by intermediate behavior, with a peak incidence in the fifth and sixth decades of life. SFTs have been reported at almost every anatomic site, with approximately 20% of cases involving the abdominal cavity. SFTs are often asymptomatic
Fibroblast Activation Protein α-Directed Imaging and Therapy of SolitaryFibrousTumor. Fibroblast activation protein α (FAPα) is expressed at high levels in several types of tumors. Here, we report the expression pattern of FAPα in solitaryfibroustumor (SFT) and its potential use as a radiotheranostic target. We analyzed FAPα messenger RNA and protein expression in biopsy samples from SFT
Intracranial solitaryfibroustumor/hemangiopericytomas: a clinical analysis of a series of 17 patients. Solitaryfibroustumors (SFTs) and haemangiopericytomas (HPCs) are rare mesenchymal tumors in central nervous system (CNS). Although progressed recognition to the diagnosis and treatment of SFT/HPCs, it still remains many confusions regarding on its occurrence, aggressive evolution, malignant
Deep learning radiomic nomogram outperforms the clinical model in distinguishing intracranial solitaryfibroustumors from angiomatous meningiomas and can predict patient prognosis. To evaluate the value of a magnetic resonance imaging (MRI)-based deep learning radiomic nomogram (DLRN) for distinguishing intracranial solitaryfibroustumors (ISFTs) from angiomatous meningioma (AMs
Solitaryfibroustumors of the oral and maxillofacial region: a case series from a single-center. Solitaryfibroustumor (SFT) is a rare mesenchymal lesion that has a wide anatomic distribution. However, this lesion rarely occurs in the oral or maxillofacial region. A retrospective review was performed to evaluate the clinical symptoms, radiological images, pathology and immunohistochemistry
Clinical outcomes of solitaryfibroustumors and hemangiopericytomas and risk factors related to recurrence and survival based on the 2021 WHO classification of central nervous system tumors. The authors aimed to explore the clinical outcomes and risk factors related to recurrence of and survival from solitaryfibroustumors (SFTs) and hemangiopericytomas (HPCs) that were reclassified according
Clinicopathological Characteristics of Three Cases with Recurrent Orbital SolitaryFibrousTumors: A Retrospective Study and Literature Review. Solitaryfibroustumor (SFT) is a spindle cell neoplasm that rarely occurs in orbit. This study aimed to report the clinical, imaging, and pathological features of three patients with recurrent orbital SFTs. Clinical, imaging, and pathological data
MRI-based radiomics nomogram for distinguishing solitaryfibroustumor from schwannoma in the orbit: a two-center study. To investigate the value of magnetic resonance imaging (MRI) radiomics for distinguishing solitaryfibroustumor (SFT) from schwannoma in the orbit. A total of 140 patients from two institutions were retrospectively included. All patients from institution 1 were randomized orbital SFT and schwannoma, which may help tumor management by clinicians. It is of great importance and challenging for distinguishing solitaryfibroustumor from schwannoma in the orbit. In the present study, an MRI-based radiomics nomogram were developed and independently validated, which could help the discrimination of the two entities. • It is challenging to differentiate solitaryfibroustumor
Large SolitaryFibrousTumor (SFT) of the penis- a case report and review of literature. Solitaryfibroustumors (SFTs) are very rare spindle cell neoplasms of mesenchymal origin with largely benign course of disease. Genital SFT's can be managed providing excellent functional and psychological outcomes by timely intervention. We report the largest and possibly the second only reported case
SolitaryFibrousTumor of the Pancreas: Analysis of 9 Cases With Literature Review. Solitaryfibroustumor (SFT) has been increasingly reported in various anatomic sites. However, it is still extremely rare in the pancreas. Herein, we present the first series of primary pancreatic SFTs. Nine cases of primary pancreatic SFTs were analyzed. The mean age was 60 years (36 to 76 y) with no sex
Solitaryfibroustumor: A rare lesion with an unusual paravertebral presentation. Solitaryfibroustumor (SFT) is a rare spindle-cell neoplasm [1]. Although typically originating from pleura, head and neck presentation accounts for about 6-18 % and very few cases have been described in paravertebral and posterior neck spaces [2]. Both computed tomography (CT) scans and magnetic resonance imaging
Misleading Morphologic and Phenotypic Features (Transdifferentiation) in SolitaryFibrousTumor of the Head and Neck: Report of 3 Cases and Review of the Literature. Solitaryfibroustumor (SFT) is a rare fibroblastic neoplasm with potentially malignant behavior that may develop in any anatomic site and may involve the head and neck (H&N) region as well. Although typical SFT has a relatively
SolitaryFibrousTumors of the Female Genital Tract: A Study of 27 Cases Emphasizing Nonvulvar Locations, Variant Histology, and Prognostic Factors. We report 27 solitaryfibroustumors of the female genital tract emphasizing nonvulvar locations, variant histology, and prognostic factors. The patients ranged from 25 to 78 years (most were over 40), and tumors occurred in the vulva (7), vagina (2 with recurrence. Female genital tract solitaryfibroustumors demonstrate a wide range of variant morphologies and occur in diverse sites in addition to the vulva. Tumors were often misdiagnosed as other neoplasms; thus, awareness of solitaryfibroustumors occurring at these sites is crucial in prompting staining for STAT6 to establish this diagnosis. The Demicco risk stratification system effectively predicts
Hemangiopericytoma/solitaryfibroustumor of the cranial base: a case series and literature review. Hemangiopericytomas (HPCs) are uncommon soft tissue tumors. HPCs that grow in the cranial base are rare. Therefore, skull-base surgeons tend to overlook this disease. This study aimed to increase the awareness of HPCs by summarizing case data from our institution and related publications. We also aimed to contribute to the number of reported cases for future systematic reviews of HPCs. This study included all patients who underwent surgery for HPC/solitaryfibroustumor (SFT) between August 2015 and August 2019. All surgeries were performed at Xiangya Hospital Central South University. We analyzed clinical characteristics, surgical highlights, treatment modalities, and outcomes. We included
Epithelioid and Clear Cell SolitaryFibrousTumors: Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of 13 Cases. Solitaryfibroustumors (SFTs) are ubiquitous soft tissue neoplasms known for their protean histology and potentially aggressive behavior. Although most cases are composed of a monotonous proliferation of spindle cells, some tumors show unusual cytologic features
Extrameningeal solitaryfibroustumors-surgery alone or surgery plus perioperative radiotherapy: A retrospective study from the global solitaryfibroustumor initiative in collaboration with the Sarcoma Patients EuroNet. Solitaryfibroustumor (SFT) is a rare mesenchymal malignancy. Although surgery is potentially curative, the local relapse risk is high after marginal resections. Given the lack
Extraordinarily long-inactive solitaryfibroustumor transformed to produce big insulin-like growth factor-2, leading to hypoglycemia and rapid liposarcoma growth: a case report. A high-molecular-weight form of insulin-like growth factor-2 (IGF-2), known as "big" IGF-2, is occasionally produced by various tumor types, leading to hypoglycemia. Although solitaryfibroustumor (SFT) is a rare
Robotic Resection of a Central Liver SolitaryFibrousTumor (with Video). Solitaryfibroustumor is a mesenchymal tumor rare in liver parenchyma 1 but must be considered as a differential diagnosis of a single large hepatic mass. Surgical resection is the treatment because of its potential malignancy, and previous interventions reported were open hepatectomy 2. Robotic assets could improve and median/left hepatic veins. Percutaneous biopsy confirmed diagnosis of benign liver solitaryfibroustumor. Surgical resection by left hepatectomy extended to segment 1 and median hepatic vein was planned. Da Vinci X system was docked from patient's head. Four robotic ports were placed in right hypochondrium. Two laparoscopic ports were placed for the second surgeon. Extended left hepatectomy
SolitaryFibrousTumor of the Prostate. Even though most tumors located in the prostate derive from prostatic glands, there is a long list of malignant and nonmalignant causes for prostatic growths that clinicians should be aware of. Tumors of the prostate can be grouped in epithelial, neuroendocrine, stromal, mesenchymal, hematolymphoid, and miscellaneous. Solitaryfibroustumor of the prostate