"Spermatocytic tumor"

Mixed Gonadal Germ Cell Tumor Composed of a Spermatocytic Tumor-like Component and Germinoma Arising in Gonadoblastoma in a Phenotypic Woman With a 46, XX Peripheral Karyotype: Report of the First Case. We report a unique case of gonadal mixed germ cell tumor (GCT) composed of a predominantly spermatocytic tumor (ST)-like component and a minor component of germinoma arising in gonadoblastoma

of mixed germ cell tumors, 2 cases of spermatocytic tumors, and 8 cases of lymphomas). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy rates of conventional ultrasound in diagnosing benign testicular tumors by "onion skin-like" echo (epidermoid cysts) and peripheral annular blood flow were 30.8%, 100.0%, 100.0%, 71.9% and 75.0%, respectively. All testicular ultrasound, the difference was statistically significant (p = 0.004). CEUS could accurately distinguish between benign and malignant testicular tumors, as well as differentiate specific pathological types (testicular focal infarction, epidermoid cysts, spermatocytic tumors, SLTC and lymphoma). Accurate preoperative diagnosis is critical for guiding the selection of appropriate treatment plans for different

recommendations are made: (1) Presence of GCNIS should be documented in all cases along with extent of spermatogenesis; (2) Immunohistochemical staining is optional in the following scenarios: identification of GCNIS, distinguishing embryonal carcinoma from seminoma, confirming presence of yolk sac tumor and/or choriocarcinoma, and differentiating spermatocytic tumor from potential mimics; (3) Detection of gain

, strong, stage-specific expression in the spermatocyte stage of germ cells in adult testis. The neoplastic counterpart, spermatocytic tumor, also showed strong RHAMM expression. This unique expression in testis suggests that RHAMM may function during normal testicular germ cell maturation.

Spermatocytic Seminoma: A Report of 85 Cases Emphasizing its Morphologic Spectrum Including Some Aspects not Widely Known. Spermatocytic seminoma (or, alternatively, spermatocytic tumor) of the testis is rare and errors in pathologic diagnosis are still made. As it has a good prognosis, except when it, rarely, undergoes sarcomatous transformation, accurate diagnosis and differentiating it from

seminoma at imaging. Benign mimics include segmental infarction, hematoma, infection, epidermoid cyst, adrenal rests, sarcoidosis, splenogonadal fusion, and sex cord-stromal tumors. Malignant mimics include nonseminomatous germ cell tumors, lymphoma, and metastases. These conditions are individually reviewed with emphasis on features that allow differentiation from seminoma. Spermatocytic tumor, formerly

: * Spermatocytic tumor[5] * Pediatric Yolk sac tumors (endodermal sinus tumour).[6] This is currently an area of controversy as some authors dispute the absence of ITGCN in these cases.[3] * Teratoma (rare exceptions)[3]Diagnosis[edit]GCNIS is not palpable, and not visible on macroscopic examination of testicular tissue. Microscopic examination of affected testicular tissue most commonly shows germ cells Germ cell G * Seminoma * Spermatocytic tumor * Germ cell neoplasia in situ

removal of one testicle. However, fertility usually isn't affected. All other sexual functions will remain intact.Contents * 1 Signs and symptoms * 2 Diagnosis * 2.1 Relation to spermatocytic tumor * 3 Treatment * 4 References * 5 External linksSigns and symptoms[edit]The average age of diagnosis is between 35 and 50 years. This is about 5 to 10 years older than men with other germ cell tumors separating the clusters of tumor cells. * Orchidectomy specimen showing seminoma * The germ cell markers OCT 3/4 and CD117 (positive immunohistochemistry pictured) are useful for diagnosis.[9] Relation to spermatocytic tumor[edit]Spermatocytic tumors are not considered a subtype of seminoma and unlike other germ cell tumours do not arise from intratubular germ cell neoplasia.[10]Treatment

Spermatocytic seminoma Spermatocytic tumor - WikipediaSpermatocytic tumorFrom Wikipedia, the free encyclopedia(Redirected from Spermatocytic seminoma)Jump to navigationJump to searchRelatively benign tumour of the testisMedical conditionSpermatocytic tumor Other names Spermatocytic tumour Micrograph of a spermatocytic tumor. H&E stain. Specialty Pathology, urology Spermatocytic tumor, previously called spermatocytic seminoma, is a neoplasm of the testis (i.e. a tumour of the testis), and classified as a germ cell tumour.The name of the tumour comes from the similarity (under the microscope) between the small cells

Systematic literature review and meta-analysis of treatment outcomes in patients with localised and metastatic spermatocytic tumors of the testis Systematic literature review and meta-analysis of treatment outcomes in patients with localised and metastatic spermatocytic tumors of the testis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has

Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline. Adult male germline stem cells (spermatogonia) proliferate by mitosis and, after puberty, generate spermatocytes that undertake meiosis to produce haploid spermatozoa. Germ cells are under evolutionary constraint to curtail mutations and maintain genome integrity . Despite constant turnover, spermatogonia very rarely form tumors, so-called spermatocytic tumors (SpT). In line with the previous identification of FGFR3 and HRAS selfish mutations in a subset of cases, candidate gene screening of 29 SpTs identified an oncogenic NRAS mutation in two cases. To gain insights in the etiology of SpT and into properties of the male germline, we performed whole-genome

(carcinoma in situ) * Specified types * Tumors of one histologic type (pure forms) * Seminoma * Variant - Seminoma with syncytiotrophoblastic cells * Spermatocytic tumor * Variant - spermatocytic tumor with sarcoma * Embryonal carcinoma * Yolk sac tumor * Trophoblastic tumors * Choriocarcinoma * Variant , it has three peaks: infancy through the age of four as teratomas and yolk sac tumors, ages 25–40 years as post-pubertal seminomas and nonseminomas, and from age 60 as spermatocytic tumors.[49]Germ cell tumors of the testis are the most common cancer in young men between the ages of 15 and 35 years.[50]United States[edit]In the United States, about 8,900 cases are diagnosed a year.[3] The risk