Intraosseous spindlecelllipoma of the maxilla: case report and review of the literature. Intraosseous lipomas are rare benign tumors of mesenchymal origin, particularly unusual in the maxilla. Spindlecelllipomas, a histological subtype, are even more uncommon, with limited cases reported in the literature. This report documents a rare case of intraosseous spindlecelllipoma in the anterior -defined radiolucency; however, the lesions may appear multilocular and may range from radiolucent to mixed radiolucent-radiopaque to 'ground glass'. Surgical excision or enucleation was the most common treatment. Intraosseous spindlecelllipomas are exceedingly rare. Based on the available evidence, surgical excision is the recommended treatment with a favorable prognosis and low recurrence rate.
Spindlecelllipoma of the larynx: A case report. Lipomas are rarely found in primary mesenchymal tumors of the hypopharynx and larynx. When they do appear, they often macroscopically resemble a retention cyst or laryngeal nodule. The laryngeal spindlecelllipoma, a variant, is extremely rare. A 65-year-old woman presented with a 3-month history of pharyngeal paraesthesia. Laryngoscopy revealed the presence of a well-encapsulated, smooth-surfaced, yellowish, pedicled mass on the left epiglottis. Magnetic resonance imaging confirmed the epiglottic mass. Following excision of the mass, the diagnosis of an spindlecelllipoma was established and confirmed by immunohistochemistry. Surgical excision of the lesion using a controlled-temperature plasma technique (coblation). At the last (4-year) follow-up
SpindleCellLipomas of the Respiratory Tract: A Case Report and Comprehensive Literature Review. Spindlecelllipomas (SCLs) are benign tumors that are characteristically present on the upper back and neck, but in rare cases present throughout the respiratory mucosa, causing hoarseness, stridor, dyspnea, and obstruction. To highlight the importance of considering SCL in the diagnosis of benign and oropharynx, the most common location described is the larynx. All 26 cases were treated with excision. One tumor required a second surgery, but there were no other complications nor recurrences. Although rare, SCLs may arise from throughout the respiratory tract and cause dyspnea, hoarseness and stridor. Spindlecelllipoma should be considered in the differential diagnosis of a respiratory tract mass
Intrathoracic Myxoid SpindleCellLipoma, A Rare Presentation of a Myxoid Neoplasm. Here we present the case of a 38-year-old man with an incidentally found right upper lobe lung mass. The patient underwent thoracoscopic resection of the mass, which revealed a myxoid spindlecelllipoma. That is an exceedingly rare location for this tumor biology, and here we discuss its pathologic features
SpindleCellLipoma of the Thumb We report the case of a 34-year-old man who presented with a 4-year history of a soft tissue on the palmar aspect of the thumb. Magnetic resonance imaging demonstrated the presence of a mass with heterogeneous high intensities on T1-weighted images and high intensities on T2-weighted images. We performed excisional biopsy. Histologically, the tumor was composed of mature adipocytes and spindle cells in a collagen background. Immunohistochemically, the tumor cells showed strong expression of CD34. Therefore, we diagnosed it as spindlecelllipoma. To the best of our knowledge, only 2 cases of spindlecelllipoma of the thumb have previously been reported.
SpindleCellLipomas in Women: A Report of 53 Cases. Spindlecelllipomas (SCL) are typically tumors of the upper back/neck (shawl region) of men (80% to 90%). In general, there is a frequent tendency to restrict the diagnosis to this specific clinical scenario and a hesitancy to diagnose SCL in women. We hypothesized that SCL in women have a more varied presentation. A total of 395 SCL were
Molecular Signature of Tumors with Monoallelic 13q14 Deletion: a Case Series of SpindleCellLipoma and Genetically-Related Tumors Demonstrating a Link Between FOXO1 Status and p38 MAPK Pathway Spindle cell/pleomorphic lipomas (SCLs), cellular angiofibromas (CAFs) and mammary-type myofibroblastomas (MFBs) are rare benign mesenchymal tumors with monoallelic 13q14 deletion. They are predicted
Loss of chromosome 13 material in cellular angiofibromas indicates pathogenetic similarity with spindlecelllipomas Cellular angiofibroma is a rare benign mesenchymal neoplasm with morphological and immunohistochemical similarities to spindlecelllipoma. Karyotypic information on cellular angiofibroma is restricted to one case only which showed loss of material from chromosomes 13 and 16 of chromosome 13 material was seen, together with other structural chromosome abnormalities. FISH analysis showed heterozygous deletion of the RB1 locus (13q14) in both cases. Our results demonstrate loss of chromosome 13 material in cellular angiofibroma, though not as the sole cytogenetic change, confirming the (cyto)genetic similarity of these tumors with spindlecelllipomas.
Cytohistological Features of SpindleCellLipoma- A Case Report with Differential Diagnosis SpindleCellLipoma (SCL) is an uncommon benign tumour of adipose tissue that is usually superficially located in the neck, back and shoulder region. Although it has characteristic histological features it can pose a diagnostic dilemma on cytology. It presents with a mixture of spindle cells, adipocytes
Spindlecelllipoma of the wrist, occurring in a distinctly rare location: a case report with review of literature Spindlecelllipoma (SCL) is a rare, benign adipocytic tumor commonly arising in the upper neck, back, and shoulder regions. To the best of our knowledge, only one case of SCL of the wrist has previously been reported. We herein report a rare case of SCL arising at the wrist. A 77
Oral SpindleCellLipoma in a Rare Location: A Differential Diagnosis Spindlecelllipoma (SCL) is an uncommon and histologically distinct variant of lipoma. It usually occurs as a solitary, subcutaneous, and well-circumscribed lesion in the posterior neck, shoulders, and back of older men. SCL of the oral cavity is rare. We present the clinical-pathologic features of the third case of SCL positive to CD34 and negative to factor VIII, alpha-smooth muscle actin, S100, cytokeratin, and actin. Mitotic activity was low, as confirmed by Ki-67 immunostaining. No lipoblastic activity was found. The diagnosis of SCL was therefore established. Oral spindlecelllipoma is a rare benign lipomatous tumor. The histologic picture shows a range of variations and the observation of morphological features
“Low-Fat†Pseudoangiomatous SpindleCellLipoma: A Rare Variant With Loss of 13q14 Region Spindle cell and pleomorphic lipoma constitute a spectrum of lipomatous lesions with characteristic clinical, morphologic, immunohistochemical, and molecular features. Multiple variants have been previously described including vascular, fibrous, plexiform, and those with significantly less fat termed "low-fat" and "fat-free" by Folpe. Cytogenetically, spindlecelllipomas frequently display monoallelic loss of 13q14 region, an abnormality also found in cellular angiofibroma and mammary-type myofibroblastoma. Pseudoangiomatous spindlecelllipoma, originally described by Fletcher et al in 1994, is a rare variant within the spindle cell/pleomorphic lipoma spectrum, with less than 20 published cases
Folliculosebaceous Cystic Hamartoma With SpindleCellLipoma-Like Stromal Features Folliculosebaceous cystic hamartoma is a distinctive cutaneous hamartoma composed of follicular, sebaceous, and mesenchymal components. The lesions are most commonly found on the face and scalp of young adults, with approximately 30% occurring in the nasal or paranasal regions of the face. The clinical differential of mucin, and bundles of ropey collagen resembling a spindlecelllipoma. This combination of a folliculosebaceous cystic hamartoma with a spindlecelllipoma-like mesenchymal proliferation is unusual and has not been previously reported.
Spindlecelllipoma masquerading as lipomatous pleomorphic adenoma: A diagnostic dilemma on fine needle aspiration cytology Spindlecelllipoma is a relatively uncommon benign adipocytic tumor that usually presents in subcutaneous fat of adult men. These are a rare form of lipoma, accounting for 1.5% of all lipomatous tumors, with a low rate of local recurrence and no risk of malignant behavior /dedifferentiation. Although few studies addressing the histological findings of spindlecelllipoma have been described, only a few descriptions of fine needle aspiration cytology (FNAC) findings have been documented in literature. We present a case of a 55-year-old male with a nodular swelling over left cheek (in the parotid region), which due to its location as well as prominent myxoid background prompted us
Myofibroblastoma of the Female Breast with Admixed but Distinct Foci of SpindleCellLipoma: A Case Report Mammary myofibroblastoma (MFB) is a rare benign spindle neoplasm that affects both sexes with a male predominance. It can exhibit a wide range of histological patterns. We report a case of epithelioid/spindle MFB of the female breast with admixed, but distinct, foci of spindlecelllipoma
Dysphagia Caused by SpindleCellLipoma of Hypopharynx: Presentation of Clinical Case and Literature Review Spindlecelllipoma of the hypopharynx is an extremely rare entity. Here, we present the first case of this lesion originated in the cricopharyngeal region, with symptoms of chronic progressive dysphagia, which can be confused with other pathologies; endoscopic and magnetic resonance
spindle cell lipomatous tumours (ASCLT), 20 cellular angiofibromas, 10 cases each of spindlecelllipoma, neurofibroma, malignant peripheral nerve sheath tumour, superficial angiomyxoma, cellular myxoma, soft tissue perineurioma and deep fibrous histiocytoma, and nine cases each of low-grade fibromyxoid sarcoma and mammary-type myofibroblastoma. We found CYP1A1 IHC to be 70% sensitive for AFST
Neurol. 2014 Jun. 29 (6):846-9. [QxMD MEDLINE Link]. 6. Choi JW, Kim HJ, Kim J, Kim HJ, Cha JH, Kim ST. Spindlecelllipoma of the head and neck: CT and MR imaging findings. Neuroradiology. 2013 Jan. 55 (1):101-6. [QxMD MEDLINE Link]. 7. Koyanagi I, Hida K, Iwasaki Y, Isu T, Yoshino M, Murakami T, et al. Radiological findings and clinical course of conus lipoma: implications