"Thyrotoxic myopathy"

Immunometabolic signatures predict recovery from thyrotoxic myopathy in patients with Graves' disease. Thyroid hormone excess induces protein energy wasting, which in turn promotes muscle weakness and bone loss in patients with Graves' disease. Although most studies have confirmed a relationship between thyrotoxicosis and muscle dysfunction, few have measured changes in plasma metabolites and immune cells during the development and recovery from thyrotoxic myopathy. The aim of this study was to identify specific plasma metabolites and T-cell subsets that predict thyrotoxic myopathy recovery in patients with Graves' disease. One hundred patients (mean age, 40.0 ± 14.2 years; 67.0% female), with newly diagnosed or relapsed Graves' disease were enrolled at the start of methimazole treatment

Thyrotoxicosis Presenting as Unilateral Drop Foot Neuromuscular disorders associated with hyperthyroidism have several variations in their clinical phenotype, such as ophthalmopathy, periodic paralysis, and thyrotoxic myopathy. We herein report an unusual case of thyrotoxic myopathy presenting as unilateral drop foot. Histopathological examinations of the left tibialis anterior muscle showed

hormone (TSH) (<0.01), high free T3 (19.2 pmol/L), and high free T4 (39.2 pmol/L). Thyroid ultrasonography, anti-thyroid peroxidase, and anti-thyroglobulin antibody were normal. Patient was treated with anti-thyroid drugs, with which he completely recovered in 2 months. Though many cases with thyrotoxic myopathy have been reported, only few mention neuropathic cause of dysphagia or polyneuritis

Myopathies of endocrine disorders: A prospective clinical and biochemical study MAJOR CATEGORIES OF ENDOCRINE MYOPATHY INCLUDE THOSE ASSOCIATED WITH: Adrenal dysfunction (as in Cushing's disease or steroid myopathy); thyroid dysfunction (as in myxedema coma or thyrotoxic myopathy); vitamin D deficiency; parathyroid dysfunction; and pituitary dysfunction. Steroid myopathy is the most common

with thyroid hormone deficiency. [15, 16, 17] Thyroid hormone excess, or thyrotoxicosis, may result from Graves disease, toxic multinodular goiter, toxic adenoma, thyroiditis, exogenous thyroid hormone intake and, rarely, excessive thyroid-stimulating hormone (TSH) secretion from the pituitary gland. [14] ​ Thyrotoxic myopathy may be secondary to a disturbance in the function of the muscle fibers from for various endocrine myopathies are as follows: * * Adrenal dysfunction: Although most cases of muscle weakness related to glucocorticoid excess resolve with therapy, there have been reports of persistent symptoms years after treatment. [35, 7] * * Thyroid dysfunction: Thyrotoxic myopathy resolves completely with treatment of the underlying endocrinopathy. However, in hypothyroid myopathy, while CK

with thyroid hormone deficiency. [15, 16, 17] Thyroid hormone excess, or thyrotoxicosis, may result from Graves disease, toxic multinodular goiter, toxic adenoma, thyroiditis, exogenous thyroid hormone intake and, rarely, excessive thyroid-stimulating hormone (TSH) secretion from the pituitary gland. [14] ​ Thyrotoxic myopathy may be secondary to a disturbance in the function of the muscle fibers from for various endocrine myopathies are as follows: * * Adrenal dysfunction: Although most cases of muscle weakness related to glucocorticoid excess resolve with therapy, there have been reports of persistent symptoms years after treatment. [35, 7] * * Thyroid dysfunction: Thyrotoxic myopathy resolves completely with treatment of the underlying endocrinopathy. However, in hypothyroid myopathy, while CK

of neuromuscular transmission) and blocking.[3]Blood tests may be performed to exclude other causes of muscle disease (elevated creatine kinase may indicate a myositis, and abnormal thyroid function tests may indicate thyrotoxic myopathy). Antibodies against voltage-gated calcium channels can be identified in 85% of people with EMG-confirmed LEMS.[3] Once LEMS is diagnosed, investigations such as a CT scan

Muscular Atrophy and Weakness in Thyrotoxicosis (Thyrotoxic Myopathy; Exophthalmic Ophthalmoplegia)

Thyrotoxic myopathy.

. The involvement of the proximal leg muscle is also interpreted as a neuropathic or nerve-mediated process rather than a concomitant thyrotoxic myopathy.

ELECTROMYOGRAPHIC AND ENDOCRINE STUDIES IN CHRONIC THYROTOXIC MYOPATHY

Chronic Thyrotoxic Myopathy with Involvement of Respiratory and Bulbar Muscles

3-Methylhistidine excretion as an index of myofibrillar protein catabolism in neuromuscular disease. Myofibrillar protein catabolism has been calculated in a variety of neuromuscular diseases from the amount of 3-methylhistidine excreted in the urine. It was found to be significantly raised in Duchenne type muscular dystrophy, motor neurone disease, polymyositis, and thyrotoxic myopathy

Thyrotoxic myopathy.

Thyrotoxic Myopathy : One case precipitated by pregnancy(?)

Thyrotoxic Myopathy

Chronic Thyrotoxic Myopathy

THYROTOXIC MYOPATHY