"Tropical sprue"

Tropical sprue Skip to main contentSkip to searchAbout usHelpSubscribeAccess through your institutionLog inBMJ Best PracticeSearchSearchSelect languageTropical sprue MENULog in or subscribe to access all of BMJ Best PracticeLast reviewed:17 Apr 2023Last updated:20 Apr 2023SummaryTropical sprue should be considered in any patient with diarrhoea and signs and/or symptoms of malabsorption who has

Tropical sprue Tropical sprue - Symptoms, diagnosis and treatment | BMJ Best PracticeSkip to main contentSkip to search * About us * Help * Subscribe * Access through your institution * Log inBMJ Best Practice * Help * Getting started * FAQs * Contact us * Recent updates * Specialties * Calculators * Patient leaflets * Videos * Evidence * Drugs * Recent updates * Specialties

Acute myocardial infarction in a young adult with hyperhomocysteinaemia secondary to tropical sprue. Coronary heart disease and its complications remain the most common cause of morbidity and mortality throughout the world. In addition, its incidence among adults <45 years of age has also been steadily increasing in the past few decades. Besides the typical aetiology such as coronary artery myocardial infarction (IWMI) in the setting of hyperhomocysteinaemia secondary to vitamin B12-folate deficiency itself due to tropical sprue.

Tropical Sprue We value your privacyWe and our partners store and/or access information on a device, such as cookies and process personal data, such as unique identifiers and standard information sent by a device for personalised ads and content, ad and content measurement, and audience insights, as well as to develop and improve products. With your permission we and our partners may use precise to be an infective one. The causative agent is, however, unclear, although it is probably bacterial. Tropical sprue is seen in residents of, and visitors to, tropical areas and it tends to begin with an acute episode of diarrhoea, fever and malaise before settling into a more chronic presentation of steatorrhea, malabsorption, nutritional deficiency, anorexia, malaise and weight loss. Folate deficiency

Post-infectious IBS, tropical sprue and small intestinal bacterial overgrowth: the missing link. Evidence is emerging that IBS, a hitherto enigmatic disorder thought to be predominantly related to psychological factors, has a microorganic basis in a subset of patients with the disease. Post-infectious IBS (PI-IBS), commonly of the diarrhoea-predominant subtype (defined as new development of IBS following acute infectious diarrhoea), is one such condition known to occur in up to 10-30% individuals after acute gastroenteritis. However, following acute infectious gastroenteritis, patients can also develop post-infectious malabsorption syndrome (PI-MAS), popularly known as tropical sprue. As no study on PI-IBS has rigorously excluded tropical sprue by appropriate investigations, including small

Tropical Sprue: Revisiting an Underrecognized Disease. Tropical sprue is an acquired chronic diarrheal disorder of unclear etiology affecting residents of and visitors to tropical regions. Patients usually present with profuse diarrhea, weight loss, and malabsorption, notably of vitamin B12 and folate. The histologic changes typically resemble that of gluten-sensitive enteropathy. Reports of tropical sprue have become infrequent in the literature, and the diagnosis is often not considered either clinically or pathologically. This disease may, however, cause significant morbidity, although it is eminently treatable with broad-spectrum antibiotics. In this study, we report the clinical presentation of 12 tropical sprue patients along with the histologic changes of the intestinal mucosa

Pathogenesis of tropical sprue: a pilot study of antroduodenal manometry, duodenocaecal transit time & fat-induced ileal brake. Small intestinal bacterial overgrowth (SIBO) due to ileal brake-induced hypomotility may cause tropical sprue (TS). We evaluated effect of infusion of fat or placebo in duodenum randomly in patients with TS and healthy controls on antroduodenal manometry (ADM

: causes include infection (e.g., HIV enteropathy, tropical sprue), systemic conditions (e.g., carcinoid syndrome), chemotherapy and radiotherapy. In infants lactase deficiency is most often secondary to infection (gastroenteritis) or cows’ milk protein allergy. Congenital lactase deficiency is an extremely rare, lifelong disorder characterised by faltering growth and intractable diarrhoea from the first

, hyperthyroidism, diabetes (may be metformin-associated), hypoparathyroidism, Addison’s disease.Cystic fibrosis.Factitious diarrhoea — the person adds water to their stools or uses laxatives. Small bowel enteropathy (for example, Whipple’s disease, tropical sprue, amyloid).Hormone-secreting tumours (for example, VIPoma, gastrinoma, carcinoid).Autonomic neuropathy.Brainerd diarrhoea (possibly due to an infectious

as persistent symptoms, signs, or laboratory abnormalities typical of CD despite 6–12 months of dietary gluten avoidance. (2) Causes of nonceliac, small-intestinal villous atrophy that may be misdiagnosed as CD include autoimmune enteropathy, tropical sprue, small-intestinal bacterial overgrowth, hypogammaglobulinemia and combined variable immunodeficiency, collagenous sprue, eosinophilic enteritis, Crohn's

, dietitian review, and detection of immunogenic peptides in stool or urine. Esophagogastroduodenoscopy with small bowel biopsies should be performed to look for villous atrophy. If villous atrophy persists or the initial diagnosis of celiac disease was not confirmed, consider other causes of villous atrophy, including common variable immunodeficiency, autoimmune enteropathy, tropical sprue, and medication . Esophagogastroduodenoscopy with small bowel biopsies should be performed to look for villous atrophy. If villous atrophy persists or the initial diagnosis of celiac disease was not confirmed, consider other causes of villous atrophy, including common variable immunodeficiency, autoimmune enteropathy, tropical sprue, and medication-induced enteropathy.If celiac disease has been confirmed, ongoing gluten ingestion, whether

., carcinomatous ascites, Budd–Chiari syndrome * Tubercles: carcinomatosis3.3.2 Intestinal tuberculosisDifferential diagnosis based on lesion type [14]: * Ulcerative: Crohn’s disease, ulcerative jejunitis (refractory celiac disease type 2), tropical sprue, immunoproliferative small-intestinal disease * Strictures: Crohn’s disease, malignancy (adenocarcinoma and lymphoma), ischemic * Hypertrophic: carcinoma

* Hyperthyroidism * Diabetes mellitus * Radiation enteritis/colitis * Eosinophilic enteritis * Chronic ischaemic colitis * Surgical bypass or resectionFull detailsUncommon * Non-steroidal anti-inflammatory drug enteropathy * Infiltrating malignancy * Protein-losing enteropathy * Graft-versus-host disease * Hodgkin's lymphoma * Non-Hodgkin's lymphoma * Tropical sprue * Lymphangiectasia/impaired lymphatic drainage

lymphoma * Disseminated chronic myelogenous leukaemia * Ulcerative colitis * Crohn's disease * Primary biliary cholangitis * Cirrhosis * Thyroid cancer * Thymus cancer * Lipoid pneumonia * Pulmonary artery sarcoma * Ulcerative oesophagitis * Achalasia * Coeliac disease * Tropical sprue * Leiomyoma of the oesophagus * Familial clubbing * Pachydermoperiostosis (primary hypertrophic osteoarthropathy

Pharmacol Ther. 2008 Jan 15;27(2):93-103.http://www.ncbi.nlm.nih.gov/pubmed/17956597?tool=bestpractice.com Less often lactase deficiency is secondary to small bowel injury: causes include infection (e.g., HIV enteropathy, tropical sprue), systemic conditions (e.g., carcinoid syndrome), chemotherapy and radiotherapy. In infants lactase deficiency is most often secondary to infection (gastroenteritis

Pharmacol Ther. 2008 Jan 15;27(2):93-103.http://www.ncbi.nlm.nih.gov/pubmed/17956597?tool=bestpractice.com Less often lactase deficiency is secondary to small bowel injury: causes include infection (e.g., HIV enteropathy, tropical sprue), systemic conditions (e.g., carcinoid syndrome), chemotherapy and radiotherapy. In infants lactase deficiency is most often secondary to infection (gastroenteritis

bacterial overgrowth ►Mesenteric ischaemia ►Lymphoma ►Surgical causes (eg, small bowel resections, faecal incontinence, internal fistulae) ►Chronic pancreatitis ►Radiation enteropathy ►Pancreatic carcinoma ►Hyperthyroidism ►Diabetes ►Giardiasis (and other chronic infection) ►Cystic fibrosisrare ►Other small bowel enteropathies (eg, Whipple’s disease, tropical sprue, amyloid, intestinal lymphangiectasia

enteropathy, tropical sprue, and medication-induced enteropathy. BEST PRACTICE ADVICE 3: For patients with nonresponsive celiac disease, after exclusion of gluten ingestion, perform a systematic evaluation for other potential causes of symptoms, including functional bowel disorders, microscopic colitis, pancreatic insufficiency, inflammatory bowel disease, lactose or fructose intolerance, and small

Tropical Sprue Tropical Sprue - Gastrointestinal Disorders - MSD Manual Professional Edition MSD Manual Please confirm that you are a health care professionalYes No Leave this Site? The link you have selected will take you to a third-party website. We do not control or have responsibility for the content of any third-party site.Continue Cancel honeypot link Brought to you by * about MSD * MSD : verify here. Medical Topics & Chapters * A * B * C * D * E * F * G * H * I * J * K * L * M * N * O * P * Q * R * S * T * U * V * W * X * Y * Z 1. Professional / 2. Gastrointestinal Disorders / 3. Malabsorption Syndromes / 4. ... / 5. Tropical Sprue / * * * * * OTHER TOPICS IN THIS CHAPTER Overview of Malabsorption Carbohydrate

, collagenous sprue, and tropical sprue. However, there are often subtle histological differences from coeliac disease in the type of inflammatory infiltrate, the presence of crypt apoptosis, and the extent and type of inflammation beyond the duodenum. The clinical setting and serological investigation usually allow diagnostic separation, but some cases remain challenging. Histopathology is also important