High-Dose Propranolol for Severe and Chronic Aggression in Autism Spectrum Disorder: A Pilot, Double-Blind, Placebo-Controlled, Randomized Crossover Study. Despite the use of behavioral interventions and psychotropic medications, many individuals with autism spectrum disorder (ASD) who engage in severe aggression remain refractory to conventional treatment. Propranolol, a beta-blocker, has
Toxoplasma gondii Infection and Aggression in Autistic Children. Toxoplasmosis is an infectious disease caused by the obligatory intracellular parasite Toxoplasma gondii. The main aim of this study was to evaluate a possible relationship between aggression in autistic children with infection by T. gondii. The research design was an analytical (comparative) cross sectional study. The participants
Aggression in autism spectrum disorder: presentation and treatment options Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by persistent difficulties in social communication and social interaction, coupled with restricted, repetitive patterns of behavior or interest. Research indicates that aggression rates may be higher in individuals with ASD compared to those
Gonadotropin-releasing hormone agonist against severe aggression in autism Aggression in patients with autism spectrum disorder (ASD) presents an important therapeutic challenge. Conventional treatment appears to be inadequate in a number of cases. The occurrence of severe aggressive symptoms since the inception of adolescence in a male patient with ASD suggested a hormonal influence by androgens
Template to Perpetrate: An Update on Violence in Autism Spectrum Disorder For the past two decades, researchers have been using various approaches to investigate the relationship, if any, between autism spectrum disorder (ASD) and violence. The need to clarify that relationship was reinforced by the tragic mass shooting at Sandy Hook Elementary School in Newtown, Connecticut, in December 2012
Gender-based violence in autism spectrum disorder: A systematic review Gender-based violence in autism spectrum disorder: A systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission
to) aggressive behaviours, autism spectrum disorders, anxiety, depression or intellectual disabilities known as TAND (Tuberous Sclerosis Associated Neuropsychiatric Disorders). • Current approaches for management of facial angiofibromas include topical ointments and invasive treatments like dermabrasion, laser therapy and surgical removal of the large lesions. However, many patients also have learning
this on TwitterShare on LinkedInShare on Google+Mark as readShare this post: Share on FacebookTweet this on TwitterShare on LinkedInShare on Google+Share via emailCreate a personal elf note about this blogTagged with: adults, aggression, aggressive behaviour, autism, autism spectrum disorder, challenging behaviour, child and adolescent, complex interventions, conduct problems, dementia, intellectual disabilities
to report it affected academic performance (80.4% vs. 36.0%, < 0.001). At both low and high levels of depression, sense of belonging was protective against physical and sexual victimization for autistic students more than for non-autistic students. : Institutions of higher education should prioritize preventing and responding to interpersonal aggression against autistic students.
epilepsies.[4]Males are affected five times more often than females.PresentationLanguage is frequently affected, with both slowness in ideation and expression in addition to difficulties of motor dysfunction. Severe behavioural disorders (eg, hyperactivity, aggressiveness and autistic tendencies) and personality disorders are nearly always present. There is also a tendency for psychosis to develop
, was treated with risperidone with complete resolution of skin-picking symptoms. risperidone has been approved for irritability and aggression in Autistic spectrum disorder, and may be a valuable treatment option for skin-picking in pediatric patients with developmental disabilities.
significant improvement. Additional placebo-controlled trials are needed to increase the number of therapeutic options available in the treatment of aggression in autism.
function, language, mathematics and visuospatial abilities. Behavioral anomalies can be mild (e.g. anxiety, mood instability) to severe (e.g. aggressive behavior, autism). Autistic-like behavior can include hand flapping, poor eye contact, hand biting, gaze avoidance, social phobia, social and communication deficits and tactile defensiveness. In females, intellectual and behavioral disorders
the Overt Aggression Scale (OAS) in a preliminary sample of eight outpatients who participated in an ongoing placebo-controlled study of valproate for aggression in autism. Subjects' OAS aggression scores showed significant correlation with the already validated retrospectively rated Aberrant Behavior Checklist Community Scale irritability subscale. Further study of the OAS in outpatients with aggression
have rarely been reported. Language is frequently affected, with both slowness in ideation and expression in addition to difficulties of motor dysfunction. Severe behavioural disorders (for example hyperactivity, aggressiveness and autistic tendencies) and personality disorders are nearly always present. There is also a tendency for psychosis to develop with time. The long-term prognosis is poor
adulthood have rarely been reported. Language is frequently affected with both slowness in ideation and expression in addition to difficulties of motor dysfunction. Severe behavioural disorders (for example hyperactivity, aggressiveness and autistic tendencies)and personality disorders are nearly always present. There is also a tendency for psychosis to develop with time. The long-term prognosis is poor
[Comparative study using double-blind method of sultopride and thioproperazine]. This report includes a statistical analysis of the results of a double blind comparative study between sultopride and thioproperazine. Two rating scales were used: the standard B.P.R.S. and a simplified scale including 7 items: agitation--delusion--thought-disorganization--anxiety--aggressivity--hallucinations --autism. The comparison of the mean of the global scores obtained with the two rating scales shows a significant difference in activity in favour of sultopride. The analysis of the individual items shows regular modifications in favour of sultopride but these are not statistically significant. There are, also, no differences in the side-effects observed, particularly extra-pyramidal effects.
on lithium and Findling reported similar findings in similar outpatients treated with risperidone. The key feature of irritable mood swings is not directly addressed in these studies. In addition, other studies of childhood aggression in Autism, Tourette Syndrome, Bipolar Disorder and mental deficiency suggest a role for risperidone. Nonetheless, it is still not clear what alternative pharmacological